Gap junctions MS Nielsen, LN Axelsen, PL Sorgen, V Verma, M Delmar, ... Comprehensive physiology 2 (3), 2012 | 550 | 2012 |
Identification of ischemia-regulated phosphorylation sites in connexin43: a possible target for the antiarrhythmic peptide analogue rotigaptide (ZP123) LN Axelsen, M Stahlhut, S Mohammed, BD Larsen, MS Nielsen, ... Journal of molecular and cellular cardiology 40 (6), 790-798, 2006 | 163 | 2006 |
Managing the complexity of communication: regulation of gap junctions by post-translational modification LN Axelsen, K Calloe, NH Holstein-Rathlou, MS Nielsen Frontiers in pharmacology 4, 130, 2013 | 155 | 2013 |
Cardiac and metabolic changes in long-term high fructose-fat fed rats with severe obesity and extensive intramyocardial lipid accumulation LN Axelsen, JB Lademann, JS Petersen, NH Holstein-Rathlou, T Ploug, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2010 | 101 | 2010 |
Sphingosine-1-phosphate reduces ischaemia–reperfusion injury by phosphorylating the gap junction protein Connexin43 S Morel, C Christoffersen, LN Axelsen, F Montecucco, V Rochemont, ... Cardiovascular research 109 (3), 385-396, 2016 | 69 | 2016 |
Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis LN Axelsen, K Calloe, TH Braunstein, M Riemann, JP Hofgaard, B Liang, ... Cardiovascular diabetology 14, 1-14, 2015 | 68 | 2015 |
Treatment of cardiac conditions JS Petersen, AL Kjoelbye, M Skovgaard, HD Pedersen, L Axelsen, ... US Patent App. 13/574,197, 2013 | 44 | 2013 |
Glucagon and a glucagon‐GLP‐1 dual‐agonist increases cardiac performance with different metabolic effects in insulin‐resistant hearts LN Axelsen, W Keung, HD Pedersen, E Meier, D Riber, AL Kjølbye, ... British Journal of Pharmacology 165 (8), 2736-2748, 2012 | 39 | 2012 |
Myocardial impulse propagation is impaired in right ventricular tissue of Zucker diabetic fatty (ZDF) rats KB Olsen, LN Axelsen, TH Braunstein, CM Sørensen, CB Andersen, ... Cardiovascular Diabetology 12, 1-11, 2013 | 33 | 2013 |
Antiarrhythmic mechanisms of SK channel inhibition in the rat atrium L Skibsbye, X Wang, LN Axelsen, SH Bomholtz, MS Nielsen, M Grunnet, ... Journal of cardiovascular pharmacology 66 (2), 165-176, 2015 | 32 | 2015 |
Metabolic and cardiac changes in high cholesterol–fructose-fed rats LN Axelsen, HD Pedersen, JS Petersen, NH Holstein-Rathlou, AL Kjølbye Journal of pharmacological and toxicological methods 61 (3), 292-296, 2010 | 31 | 2010 |
Increasing gap junctional coupling: a tool for dissecting the role of gap junctions LN Axelsen, K Haugan, M Stahlhut, AL Kjølbye, JK Hennan, ... Journal of Membrane Biology 216, 23-35, 2007 | 27 | 2007 |
Clopidogrel, a CYP2C8 inhibitor, causes a clinically relevant increase in the systemic exposure to the active metabolite of selexipag in healthy subjects LN Axelsen, I Poggesi, F Rasschaert, JJ Perez Ruixo, S Bruderer British Journal of Clinical Pharmacology 87 (1), 119-128, 2021 | 12 | 2021 |
Angiotensin II does not acutely regulate conduction velocity in rat atrial tissue KB Olsen, TH Braunstein, CM Sørensen, LN Axelsen, ... Scandinavian Journal of Clinical and Laboratory Investigation 71 (6), 492-499, 2011 | 11 | 2011 |
Serine 297 and serine 306: two new phosphorylation sites involved in the regulation of connexin43 during ischemia L Axelsen, S Mohammed, A Kjolbye, MS Nielsen, N Holstein-Rathlou, ... | 6 | 2005 |
Temporarily switching from oral to intravenous selexipag in patients with pulmonary arterial hypertension: safety, tolerability, and pharmacokinetic results from an open-label … H Klose, KM Chin, R Ewert, H Gall, J Parambil, D Poch, HJ Seyfarth, ... Respiratory Research 22, 1-9, 2021 | 5 | 2021 |
Safety, tolerability and pharmacokinetics study in patients with pulmonary arterial hypertension (PAH) temporarily switching from oral to IV selexipag H Klose, K Chin, R Ewert, H Gall, J Parambil, D Poch, H Seyfarth, ... The Journal of Heart and Lung Transplantation 38 (4), S490, 2019 | 4 | 2019 |
Acute intramyocardial lipid accumulation in rats does not slow cardiac conduction per se CF Jensen, ED Bartels, TH Braunstein, LB Nielsen, NH Holstein‐Rathlou, ... Physiological Reports 7 (7), e14049, 2019 | 3 | 2019 |
Population pharmacokinetics of selexipag for dose selection and confirmation in pediatric patients with pulmonary arterial hypertension LN Axelsen, A Kümmel, JJ Perez Ruixo, A Russu CPT: Pharmacometrics & Systems Pharmacology 13 (12), 2185-2195, 2024 | | 2024 |
Diet-induced hypertension in rats is associated with increased renal vasoconstrictor response to angiotensin II after imitated endothelial dysfunction LJ Jensen, MAV Lund, M Salomonsson, JP Goetze, TE Jonassen, ... Microvascular Research 141, 104333, 2022 | | 2022 |