Novel strategies to address the challenges in top-down proteomics JA Melby*, DS Roberts*, EJ Larson, KA Brown, EF Bayne, S Jin, Y Ge, ... Journal of the American Society for Mass Spectrometry 32 (6), 1278-1294, 2021 | 163 | 2021 |
Top-down proteomics: challenges, innovations, and applications in basic and clinical research KA Brown, JA Melby, DS Roberts, Y Ge Expert Review of Proteomics, 1-15, 2020 | 126 | 2020 |
MASH explorer: a universal software environment for top-down proteomics Z Wu, DS Roberts, JA Melby, K Wenger, M Wetzel, Y Gu, SG Ramanathan, ... Journal of proteome research 19 (9), 3867-3876, 2020 | 81 | 2020 |
Structural O-Glycoform Heterogeneity of the SARS-CoV-2 Spike Protein Receptor-Binding Domain Revealed by Top-Down Mass Spectrometry DS Roberts†, M Mann, JA Melby, EJ Larson, Y Zhu, AR Brasier, S Jin, ... Journal of the American Chemical Society 143 (31), 12014–12024, 2021 | 69 | 2021 |
Nanoproteomics enables proteoform-resolved analysis of low-abundance proteins in human serum TN Tiambeng*, DS Roberts*, KA Brown, Y Zhu, B Chen, Z Wu, SD Mitchell, ... Nature communications 11 (1), 1-12, 2020 | 63 | 2020 |
Ultrafast and Reproducible Proteomics from Small Amounts of Heart Tissue Enabled by Azo and timsTOF Pro TJ Aballo, DS Roberts, JA Melby, KM Buck, KA Brown, Y Ge Journal of Proteome Research 20 (8), 4203–4211, 2021 | 56 | 2021 |
Oriented nanofibrous polymer scaffolds containing protein‐loaded porous silicon generated by spray nebulization JM Zuidema, T Kumeria, D Kim, J Kang, J Wang, G Hollett, X Zhang, ... Advanced Materials 30 (12), 1706785, 2018 | 46 | 2018 |
High-throughput multi-attribute analysis of antibody-drug conjugates enabled by trapped ion mobility spectrometry and top-down mass spectrometry EJ Larson*, DS Roberts*, JA Melby, KM Buck, Y Zhu, S Zhou, L Han, ... Analytical chemistry 93 (29), 10013-10021, 2021 | 41 | 2021 |
High sensitivity top–down proteomics captures single muscle cell heterogeneity in large proteoforms JA Melby, KA Brown, ZR Gregorich, DS Roberts, EA Chapman, LE Ehlers, ... Proceedings of the National Academy of Sciences 120 (19), e2222081120, 2023 | 35 | 2023 |
Reproducible large-scale synthesis of surface silanized nanoparticles as an enabling nanoproteomics platform: Enrichment of the human heart phosphoproteome DS Roberts, B Chen, TN Tiambeng, Z Wu, Y Ge, S Jin Nano Research 12 (6), 1473–1481, 2019 | 32 | 2019 |
Distinct core glycan and O-glycoform utilization of SARS-CoV-2 Omicron variant Spike protein RBD revealed by top-down mass spectrometry DS Roberts†, M Mann, BH Li, D Kim, AR Braiser, S Jin, Y Ge†, ... Chemical science 13 (36), 10944-10949, 2022 | 28 | 2022 |
Functionally integrated top-down proteomics for standardized assessment of human induced pluripotent stem cell-derived engineered cardiac tissues JA Melby, WJ de Lange, J Zhang, DS Roberts, SD Mitchell, T Tucholski, ... Journal of proteome research 20 (2), 1424-1433, 2021 | 23 | 2021 |
Discovery of RSV-induced BRD4 protein interactions using native immunoprecipitation and parallel accumulation—serial fragmentation (PASEF) mass spectrometry M Mann, DS Roberts, Y Zhu, Y Li, J Zhou, Y Ge, AR Brasier Viruses 13 (3), 454, 2021 | 19 | 2021 |
Preparation of Photoluminescent Porous Silicon Nanoparticles by High‐Pressure Microfluidization DS Roberts, D Estrada, N Yagi, EJ Anglin, NA Chan, MJ Sailor Particle & Particle Systems Characterization 34 (3), 1600326, 2017 | 19 | 2017 |
Top-down proteomics DS Roberts†, JA Loo, YO Tsybin, X Liu, S Wu, J Chamot-Rooke, JN Agar, ... Nature Reviews Methods Primers 4 (1), 38, 2024 | 18 | 2024 |
MASH Native: a unified solution for native top-down proteomics data processing EJ Larson, MR Pergande, ME Moss, KJ Rossler, RK Wenger, B Krichel, ... Bioinformatics 39 (6), btad359, 2023 | 18 | 2023 |
Analysis of cardiac troponin proteoforms by top-down mass spectrometry TN Tiambeng, T Tucholski, Z Wu, Y Zhu, SD Mitchell, DS Roberts, Y Jin, ... Methods in enzymology 626, 347-374, 2019 | 17 | 2019 |
Necroptosis is associated with Rab27‐independent expulsion of extracellular vesicles containing RIPK3 and MLKL K Gupta, KA Brown, ML Hsieh, BM Hoover, J Wang, MK Khoury, VSS Pilli, ... Journal of extracellular vesicles 11 (9), e12261, 2022 | 16 | 2022 |
One-pot exosome proteomics enabled by a photocleavable surfactant KM Buck, DS Roberts, TJ Aballo, DR Inman, S Jin, S Ponik, KA Brown, ... Analytical chemistry 94 (20), 7164-7168, 2022 | 16 | 2022 |
Multiomics method enabled by sequential metabolomics and proteomics for human pluripotent stem-cell-derived cardiomyocytes EF Bayne, AD Simmons, DS Roberts, Y Zhu, TJ Aballo, B Wancewicz, ... Journal of proteome research 20 (10), 4646-4654, 2021 | 15 | 2021 |