| Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2 Y Zhou, Y Hou, J Shen, Y Huang, W Martin, F Cheng Cell discovery 6 (1), 14, 2020 | 1673 | 2020 |
| New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysis Y Hou, J Zhao, W Martin, A Kallianpur, MK Chung, L Jehi, N Sharifi, ... BMC medicine 18, 1-8, 2020 | 432 | 2020 |
| Repurpose open data to discover therapeutics for COVID-19 using deep learning X Zeng, X Song, T Ma, X Pan, Y Zhou, Y Hou, Z Zhang, K Li, G Karypis, ... Journal of proteome research 19 (11), 4624-4636, 2020 | 243 | 2020 |
| A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19 Y Zhou, Y Hou, J Shen, R Mehra, A Kallianpur, DA Culver, MU Gack, ... PLoS biology 18 (11), e3000970, 2020 | 210 | 2020 |
| A genome-wide positioning systems network algorithm for in silico drug repurposing F Cheng, W Lu, C Liu, J Fang, Y Hou, DE Handy, R Wang, Y Zhao, ... Nature communications 10 (1), 3476, 2019 | 198 | 2019 |
| Comprehensive characterization of protein–protein interactions perturbed by disease mutations F Cheng, J Zhao, Y Wang, W Lu, Z Liu, Y Zhou, WR Martin, R Wang, ... Nature genetics 53 (3), 342-353, 2021 | 179 | 2021 |
| Reducing acetylated tau is neuroprotective in brain injury MK Shin, E Vázquez-Rosa, Y Koh, M Dhar, K Chaubey, CJ Cintrón-Pérez, ... Cell 184 (10), 2715-2732. e23, 2021 | 145 | 2021 |
| Endophenotype-based in silico network medicine discovery combined with insurance record data mining identifies sildenafil as a candidate drug for Alzheimer’s disease J Fang, P Zhang, Y Zhou, CW Chiang, J Tan, Y Hou, S Stauffer, L Li, ... Nature Aging 1 (12), 1175-1188, 2021 | 141 | 2021 |
| Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment Y Zhou, J Xu, Y Hou, JB Leverenz, A Kallianpur, R Mehra, Y Liu, H Yu, ... Alzheimer's research & therapy 13 (1), 110, 2021 | 141 | 2021 |
| A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets Y Zhou, Y Liu, S Gupta, MI Paramo, Y Hou, C Mao, Y Luo, J Judd, ... Nature biotechnology 41 (1), 128-139, 2023 | 138 | 2023 |
| Network-based prediction of drug–target interactions using an arbitrary-order proximity embedded deep forest X Zeng, S Zhu, Y Hou, P Zhang, L Li, J Li, LF Huang, SJ Lewis, ... Bioinformatics 36 (9), 2805-2812, 2020 | 127 | 2020 |
| Hormone and receptor interplay in the regulation of mosquito lipid metabolism X Wang, Y Hou, TT Saha, G Pei, AS Raikhel, Z Zou Proceedings of the National Academy of Sciences 114 (13), E2709-E2718, 2017 | 127 | 2017 |
| Temporal coordination of carbohydrate metabolism during mosquito reproduction Y Hou, XL Wang, TT Saha, S Roy, B Zhao, AS Raikhel, Z Zou PLoS genetics 11 (7), e1005309, 2015 | 107 | 2015 |
| Artificial intelligence framework identifies candidate targets for drug repurposing in Alzheimer’s disease J Fang, P Zhang, Q Wang, CW Chiang, Y Zhou, Y Hou, J Xu, R Chen, ... Alzheimer's Research & Therapy 14, 1-23, 2022 | 76 | 2022 |
| A systems pharmacology approach uncovers wogonoside as an angiogenesis inhibitor of triple-negative breast cancer by targeting hedgehog signaling Y Huang, J Fang, W Lu, Z Wang, Q Wang, Y Hou, X Jiang, O Reizes, ... Cell chemical biology 26 (8), 1143-1158. e6, 2019 | 74 | 2019 |
| Multimodal single-cell/nucleus RNA sequencing data analysis uncovers molecular networks between disease-associated microglia and astrocytes with implications for drug … J Xu, P Zhang, Y Huang, Y Zhou, Y Hou, LM Bekris, J Lathia, CW Chiang, ... Genome research 31 (10), 1900-1912, 2021 | 70 | 2021 |
| Hairy and Groucho mediate the action of juvenile hormone receptor Methoprene-tolerant in gene repression TT Saha, SW Shin, W Dou, S Roy, B Zhao, Y Hou, XL Wang, Z Zou, ... Proceedings of the National Academy of Sciences 113 (6), E735-E743, 2016 | 67 | 2016 |
| Integrative proteomics and phosphoproteomics in pulmonary arterial hypertension W Xu, SAA Comhair, R Chen, B Hu, Y Hou, Y Zhou, LA Mavrakis, ... Scientific Reports 9 (1), 18623, 2019 | 59 | 2019 |
| Machine learning–based risk assessment for cancer therapy–related cardiac dysfunction in 4300 longitudinal oncology patients Y Zhou, Y Hou, M Hussain, SA Brown, T Budd, WHW Tang, J Abraham, ... Journal of the American Heart Association 9 (23), e019628, 2020 | 58 | 2020 |
| Interpretable deep learning translation of GWAS and multi-omics findings to identify pathobiology and drug repurposing in Alzheimer’s disease J Xu, C Mao, Y Hou, Y Luo, JL Binder, Y Zhou, LM Bekris, J Shin, M Hu, ... Cell reports 41 (9), 2022 | 55 | 2022 |
Feixiong ChengCleveland Clinic在 ccf.org 的电子邮件经过验证