关注
Finny S. Varghese
Finny S. Varghese
Department of Medical Microbiology, Radboud University Medical Center
在 radboudumc.nl 的电子邮件经过验证
标题
引用次数
引用次数
年份
Discovery of berberine, abamectin and ivermectin as antivirals against chikungunya and other alphaviruses
FS Varghese, P Kaukinen, S Gläsker, M Bespalov, L Hanski, ...
Antiviral research 126, 117-124, 2016
2462016
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ...
Cell stem cell 29 (2), 217-231. e8, 2022
2122022
The antiviral alkaloid berberine reduces chikungunya virus-induced mitogen-activated protein kinase signaling
FS Varghese, B Thaa, SN Amrun, D Simarmata, K Rausalu, TA Nyman, ...
Journal of virology 90 (21), 9743-9757, 2016
1552016
Differential phosphatidylinositol-3-kinase-Akt-mTOR activation by Semliki Forest and chikungunya viruses is dependent on nsP3 and connected to replication complex internalization
B Thaa, R Biasiotto, K Eng, M Neuvonen, B Götte, L Rheinemann, ...
Journal of virology 89 (22), 11420-11437, 2015
1192015
Design and validation of novel chikungunya virus protease inhibitors
PK Das, L Puusepp, FS Varghese, A Utt, T Ahola, DG Kananovich, ...
Antimicrobial agents and chemotherapy 60 (12), 7382-7395, 2016
782016
Obatoclax inhibits alphavirus membrane fusion by neutralizing the acidic environment of endocytic compartments
FS Varghese, K Rausalu, M Hakanen, S Saul, BM Kümmerer, P Susi, ...
Antimicrobial agents and chemotherapy 61 (3), 10.1128/aac. 02227-16, 2017
752017
Berberine and obatoclax inhibit SARS-Cov-2 replication in primary human nasal epithelial cells in vitro
FS Varghese, E van Woudenbergh, GJ Overheul, MJ Eleveld, L Kurver, ...
Viruses 13 (2), 282, 2021
732021
Chikungunya virus infectivity, RNA replication and non-structural polyprotein processing depend on the nsP2 protease’s active site cysteine residue
K Rausalu, A Utt, T Quirin, FS Varghese, E Žusinaite, PK Das, T Ahola, ...
Scientific reports 6 (1), 37124, 2016
702016
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors
ML Boby, D Fearon, M Ferla, M Filep, L Koekemoer, MC Robinson, ...
Science 382 (6671), eabo7201, 2023
682023
Natural variation in resistance to virus infection in dipteran insects
WH Palmer, FS Varghese, RP Van Rij
Viruses 10 (3), 118, 2018
672018
COVID moonshot: open science discovery of SARS-CoV-2 main protease inhibitors by combining crowdsourcing, high-throughput experiments, computational simulations, and machine …
H Achdout, A Aimon, E Bar-David, GM Morris
BioRxiv, 2020
552020
Population genomics in the arboviral vector Aedes aegypti reveals the genomic architecture and evolution of endogenous viral elements
CM Crava, FS Varghese, E Pischedda, R Halbach, U Palatini, ...
Molecular ecology 30 (7), 1594-1611, 2021
492021
Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors
COVID Moonshot Consortium, H Achdout, A Aimon, DS Alonzi, R Arbon, ...
BioRxiv, 2020.10. 29.339317, 2020
402020
Insect virus discovery by metagenomic and cell culture-based approaches
FS Varghese, RP van Rij
Viral Metagenomics: Methods and Protocols, 197-213, 2018
102018
Natural variation in resistance to virus infection in dipteran insects. Viruses 10: 118
WH Palmer, FS Varghese, RP Van Rij
72018
Posaconazole inhibits multiple steps of the alphavirus replication cycle
FS Varghese, F Meutiawati, M Teppor, S Jacobs, C de Keyzer, ...
Antiviral research 197, 105223, 2022
62022
Posaconazole is a novel inhibitor for alphavirus viral entry
FS Varghese, F Meutiawati, M Teppor, A Merits, RP Rij
Access Microbiology 1 (10), 41, 2019
42019
Cracking the code of chikungunya virus: inhibitors as tools to explore alphavirus biology
FS Varghese
Helsingin yliopisto, 2016
22016
Chikungunya virus: Replication & Replication Inhibitors
F Varghese
系统目前无法执行此操作,请稍后再试。
文章 1–19