Design, synthesis, molecular docking and biological activity evaluation of some novel indole derivatives as potent anticancer active agents and apoptosis inducers AMS El-Sharief, YA Ammar, A Belal, MAMS El-Sharief, YA Mohamed, ... Bioorganic chemistry 85, 399-412, 2019 | 100 | 2019 |
Novel Structural hybrids of quinoline and thiazole moieties: Synthesis and evaluation of antibacterial and antifungal activities with molecular modeling studies SI Eissa, AM Farrag, SY Abbas, MF El Shehry, A Ragab, EA Fayed, ... Bioorganic Chemistry 110, 104803, 2021 | 98 | 2021 |
Design, synthesis, antiproliferative activity, molecular docking and cell cycle analysis of some novel (morpholinosulfonyl) isatins with potential EGFR inhibitory activity YA Ammar, AMS El-Sharief, A Belal, SY Abbas, YA Mohamed, ... European journal of medicinal chemistry 156, 918-932, 2018 | 94 | 2018 |
Discovery of new Schiff bases tethered pyrazole moiety: Design, synthesis, biological evaluation, and molecular docking study as dual targeting DHFR/DNA gyrase inhibitors with … AS Hassan, AA Askar, AM Naglah, AA Almehizia, A Ragab Molecules 25 (11), 2593, 2020 | 72 | 2020 |
Antimicrobial evaluation of thiadiazino and thiazolo quinoxaline hybrids as potential DNA gyrase inhibitors; design, synthesis, characterization and morphological studies YA Ammar, AA Farag, AM Ali, SA Hessein, AA Askar, EA Fayed, DM Elsisi, ... Bioorganic Chemistry 99, 103841, 2020 | 72 | 2020 |
One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor MA Salem, A Ragab, AA Askar, A El-Khalafawy, AH Makhlouf European Journal of Medicinal Chemistry 188, 111977, 2020 | 72 | 2020 |
Development of novel indolin-2-one derivative incorporating thiazole moiety as DHFR and quorum sensing inhibitors: synthesis, antimicrobial, and antibiofilm activities with … AY Alzahrani, YA Ammar, M Abu-Elghait, MA Salem, MA Assiri, TE Ali, ... Bioorganic Chemistry 119, 105571, 2022 | 65 | 2022 |
In vitro enzymatic evaluation of some pyrazolo[1,5‐a]pyrimidine derivatives: Design, synthesis, antioxidant, anti‐diabetic, anti‐Alzheimer, and anti‐arthritic activities … AS Hassan, NM Morsy, WM Aboulthana, A Ragab Drug Development Research 84 (1), 3-24, 2023 | 62 | 2023 |
Design, synthesis, in vitro antimicrobial evaluation and molecular docking studies of indol-2-one tagged with morpholinosulfonyl moiety as DNA gyrase inhibitors MA Salem, A Ragab, A El-Khalafawy, AH Makhlouf, AA Askar, YA Ammar Bioorganic chemistry 96, 103619, 2020 | 60 | 2020 |
Sulfaguanidine hybrid with some new pyridine-2-one derivatives: Design, synthesis, and antimicrobial activity against multidrug-resistant bacteria as dual DNA gyrase and DHFR … A Ragab, SA Fouad, OAA Ali, EM Ahmed, AM Ali, AA Askar, YA Ammar Antibiotics 10 (2), 162, 2021 | 57 | 2021 |
Design, synthesis, antiproliferative evaluation, and molecular docking study of new quinoxaline derivatives as apoptotic inducers and EGFR inhibitors EA Fayed, YA Ammar, MA Saleh, AH Bayoumi, A Belal, ABM Mehany, ... Journal of Molecular Structure 1236, 130317, 2021 | 56 | 2021 |
Development of adamantane scaffold containing 1, 3, 4-thiadiazole derivatives: Design, synthesis, anti-proliferative activity and molecular docking study targeting EGFR MMS Wassel, YA Ammar, GAME Ali, A Belal, ABM Mehany, A Ragab Bioorganic Chemistry 110, 104794, 2021 | 56 | 2021 |
Exploring novel derivatives of isatin-based Schiff bases as multi-target agents: design, synthesis, in vitro biological evaluation, and in silico ADMET analysis with molecular … AS Hassan, NM Morsy, WM Aboulthana, A Ragab RSC advances 13 (14), 9281-9303, 2023 | 55 | 2023 |
Discovery of novel pyrazole and pyrazolo [1, 5‐a] pyrimidine derivatives as cyclooxygenase inhibitors (COX‐1 and COX‐2) using molecular modeling simulation R Ayman, AM Radwan, AM Elmetwally, YA Ammar, A Ragab Archiv der Pharmazie 356 (2), e2200395, 2023 | 55 | 2023 |
Synthesis, characterization, thermal properties, antimicrobial evaluation, ADMET study, and molecular docking simulation of new mono Cu (II) and Zn (II) complexes with 2 … A Ragab, YA Ammar, A Ezzat, AM Mahmoud, MBI Mohamed, S Abdou, ... Computers in Biology and Medicine 145, 105473, 2022 | 55 | 2022 |
Coordination compounds of pyrazolone‐based ligand: Design, characterization, biological evaluation, antitumor efficiency, and DNA binding evaluation supported by in silico studies SA Ibrahim, A Ragab, HA El‐Ghamry Applied Organometallic Chemistry 36 (2), e6508, 2022 | 54 | 2022 |
Synthesis, spectral characterization, antimicrobial evaluation and molecular docking studies of new Cu (II), Zn (II) thiosemicarbazone based on sulfonyl isatin A Ezzat, MBI Mohamed, AM Mahmoud, RS Farag, AS El-Tabl, A Ragab Journal of Molecular Structure 1251, 132004, 2022 | 54 | 2022 |
Design, synthesis of new novel quinoxalin-2 (1H)-one derivatives incorporating hydrazone, hydrazine, and pyrazole moieties as antimicrobial potential with in-silico ADME and … A Ragab, DM Elsisi, OAA Ali, MS Abusaif, AA Askar, AA Farag, YA Ammar Arabian Journal of Chemistry 15 (1), 103497, 2022 | 54 | 2022 |
In vitro cytotoxic activity of thiazole-indenoquinoxaline hybrids as apoptotic agents, design, synthesis, physicochemical and pharmacokinetic studies EA Fayed, YA Ammar, A Ragab, NA Gohar, ABM Mehany, AM Farrag Bioorganic Chemistry 100, 103951, 2020 | 54 | 2020 |
Anticancer effects with molecular docking confirmation of newly synthesized isatin sulfonamide molecular hybrid derivatives against hepatic cancer cell lines M Eldeeb, EF Sanad, A Ragab, YA Ammar, K Mahmoud, MM Ali, ... Biomedicines 10 (3), 722, 2022 | 53 | 2022 |