| NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8 A Anandhan, M Dodson, A Shakya, J Chen, P Liu, Y Wei, H Tan, Q Wang, ... Science advances 9 (5), eade9585, 2023 | 210 | 2023 |
| Selective killing of Helicobacter pylori with pH-responsive helix–coil conformation transitionable antimicrobial polypeptides M Xiong, Y Bao, X Xu, H Wang, Z Han, Z Wang, Y Liu, S Huang, Z Song, ... Proceedings of the National Academy of Sciences 114 (48), 12675-12680, 2017 | 145 | 2017 |
| Brd4 modulates the innate immune response through Mnk2–eIF4E pathway-dependent translational control of IκBα Y Bao, X Wu, J Chen, X Hu, F Zeng, J Cheng, H Jin, X Lin, LF Chen Proceedings of the National Academy of Sciences 114 (20), E3993-E4001, 2017 | 81 | 2017 |
| BRD4 regulates cellular senescence in gastric cancer cells via E2F/miR-106b/p21 axis X Dong, X Hu, J Chen, D Hu, LF Chen Cell death & disease 9 (2), 203, 2018 | 77 | 2018 |
| Salidroside stimulates osteoblast differentiation through BMP signaling pathway JJ Chen, NF Zhang, GX Mao, XB He, YC Zhan, HB Deng, DQ Song, DD Li, ... Food and chemical toxicology 62, 499-505, 2013 | 60 | 2013 |
| BET Inhibition Attenuates Helicobacter pylori–Induced Inflammatory Response by Suppressing Inflammatory Gene Transcription and Enhancer Activation J Chen, Z Wang, X Hu, R Chen, J Romero-Gallo, RM Peek, LF Chen The Journal of Immunology 196 (10), 4132-4142, 2016 | 53 | 2016 |
| Decreased autophagosome biogenesis, reduced NRF2, and enhanced ferroptotic cell death are underlying molecular mechanisms of non-alcoholic fatty liver disease P Liu, A Anandhan, J Chen, A Shakya, M Dodson, A Ooi, E Chapman, ... Redox Biology 59, 102570, 2023 | 45 | 2023 |
| NRF2 and diabetes: the good, the bad, and the complex M Dodson, A Shakya, A Anandhan, J Chen, JGN Garcia, DD Zhang Diabetes 71 (12), 2463-2476, 2022 | 44 | 2022 |
| Phosphorylation of hepatic farnesoid X receptor by FGF19 signaling–activated Src maintains cholesterol levels and protects from atherosclerosis S Byun, H Jung, J Chen, YC Kim, DH Kim, B Kong, G Guo, B Kemper, ... Journal of Biological Chemistry 294 (22), 8732-8744, 2019 | 43 | 2019 |
| Prolyl isomerase PIN1 regulates the stability, transcriptional activity and oncogenic potential of BRD4 X Hu, SH Dong, J Chen, XZ Zhou, R Chen, S Nair, KP Lu, LF Chen Oncogene 36 (36), 5177-5188, 2017 | 41 | 2017 |
| Small molecule T63 suppresses osteoporosis by modulating osteoblast differentiation via BMP and WNT signaling pathways X Zhao, J Chen, G Zhang, Y Wang, S Si, LF Chen, Z Wang Scientific reports 7 (1), 10397, 2017 | 36 | 2017 |
| Helicobacter pylori activates NF‐κB by inducing Ubc13‐mediated ubiquitination of lysine 158 of TAK1 A Lamb, JJ Chen, SR Blanke, LF Chen Journal of cellular biochemistry 114 (10), 2284-2292, 2013 | 26 | 2013 |
| Brd4 modulates diet-induced obesity via PPARγ-dependent Gdf3 expression in adipose tissue macrophages X Hu, X Dong, G Li, Y Chen, J Chen, X He, H Sun, DH Kim, JK Kemper, ... JCI insight 6 (7), 2021 | 24 | 2021 |
| S632A3, a new glutarimide antibiotic, suppresses lipopolysaccharide-induced pro-inflammatory responses via inhibiting the activation of glycogen synthase kinase 3β H Deng, N Zhang, Y Wang, J Chen, J Shen, Z Wang, R Xu, J Zhang, ... Experimental Cell Research 318 (20), 2592-2603, 2012 | 22 | 2012 |
| BRD4 inhibition and FXR activation, individually beneficial in cholestasis, are antagonistic in combination H Jung, J Chen, X Hu, H Sun, SY Wu, CM Chiang, B Kemper, LF Chen, ... JCI insight 6 (1), e141640, 2020 | 21 | 2020 |
| Lidamycin inhibits tumor initiating cells of hepatocellular carcinoma Huh7 through GSK3β/β‐catenin pathway Y Chen, D Yu, C Zhang, B Shang, H He, J Chen, H Zhang, W Zhao, ... Molecular Carcinogenesis 54 (1), 1-8, 2015 | 20 | 2015 |
| Synthesis and biological evaluation of geldanamycin analogs against human cancer cells Y Li*, J Chen*, J Shen, J Cui, L Wu, Z Wang, Z Li Cancer chemotherapy and pharmacology 75 (4), 773-782, 2015 | 17 | 2015 |
| Methods to detect NF-κB acetylation and methylation JJ Chen, LF Chen NF-kappa B: Methods and Protocols, 395-409, 2015 | 13 | 2015 |
| T63 inhibits osteoclast differentiation through regulating MAPKs and Akt signaling pathways X Zhao, J Chen, S Si, L Chen, Z Wang European journal of pharmacology 834, 30-35, 2018 | 7 | 2018 |
| Research Progress of Pharmacological Actions and Mechanisms of Active Components of Rhodiola L． J Shen, G Mao, J Chen, Z Wang, D Li Int J Geriatr 33 (5), 206-210, 2012 | 5* | 2012 |
