| Comprehensive genomic characterization defines human glioblastoma genes and core pathways Cancer Genome Atlas Research Network Tissue source sites: Duke University ... Nature 455 (7216), 1061-1068, 2008 | 7655 | 2008 |
| VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing DC Koboldt, Q Zhang, DE Larson, D Shen, MD McLellan, L Lin, CA Miller, ... Genome Research 22 (3), 568-576, 2012 | 5123 | 2012 |
| Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia TCGAR Network New England Journal of Medicine 368 (22), 2059-2074, 2013 | 4997* | 2013 |
| Mutational landscape and significance across 12 major cancer types C Kandoth, MD McLellan, F Vandin, K Ye, B Niu, C Lu, M Xie, Q Zhang, ... Nature 502 (7471), 333-339, 2013 | 4991 | 2013 |
| Comprehensive molecular profiling of lung adenocarcinoma Cancer Genome Atlas Research Network Nature 511 (7511), 543, 2014 | 4920* | 2014 |
| Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing L Ding, TJ Ley, DE Larson, CA Miller, DC Koboldt, JS Welch, JK Ritchey, ... Nature, 2012 | 2605 | 2012 |
| Age-related mutations associated with clonal hematopoietic expansion and malignancies M Xie, C Lu, J Wang, MD McLellan, KJ Johnson, MC Wendl, ... Nature medicine 20 (12), 1472-1478, 2014 | 2041 | 2014 |
| The Origin and Evolution of Mutations in Acute Myeloid Leukemia JS Welch, TJ Ley, DC Link, CA Miller, DE Larson, DC Koboldt, ... Cell 150 (2), 264-278, 2012 | 1907 | 2012 |
| Whole-genome analysis informs breast cancer response to aromatase inhibition MJ Ellis, L Ding, D Shen, J Luo, VJ Suman, JW Wallis, BA Van Tine, ... Nature 486 (7403), 353-360, 2012 | 1232 | 2012 |
| Comprehensive and integrated genomic characterization of adult soft tissue sarcomas AJ Lazar, MD McLellan, MH Bailey, CA Miller, EL Appelbaum, MG Cordes, ... Cell 171 (4), 950-965, 2017 | 917 | 2017 |
| Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia TN Wong, G Ramsingh, AL Young, CA Miller, W Touma, JS Welch, ... Nature 518 (7540), 552-555, 2015 | 887 | 2015 |
| TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes JS Welch, AA Petti, CA Miller, CC Fronick, M O’Laughlin, RS Fulton, ... New England Journal of Medicine 375 (21), 2023-2036, 2016 | 886 | 2016 |
| Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts S Li, D Shen, J Shao, R Crowder, W Liu, A Prat, X He, S Liu, J Hoog, C Lu, ... Cell reports 4 (6), 1116-1130, 2013 | 726 | 2013 |
| DGIdb: mining the druggable genome M Griffith, OL Griffith, AC Coffman, JV Weible, JF McMichael, NC Spies, ... Nature methods 10 (12), 1209-1210, 2013 | 541 | 2013 |
| SciClone: inferring clonal architecture and tracking the spatial and temporal patterns of tumor evolution CA Miller, BS White, ND Dees, M Griffith, JS Welch, OL Griffith, R Vij, ... PLoS computational biology 10 (8), e1003665, 2014 | 522 | 2014 |
| The R882H DNMT3A mutation associated with AML dominantly inhibits wild-type DNMT3A by blocking its ability to form active tetramers DA Russler-Germain, DH Spencer, MA Young, TL Lamprecht, CA Miller, ... Cancer cell 25 (4), 442-454, 2014 | 498 | 2014 |
| Functional heterogeneity of genetically defined subclones in acute myeloid leukemia JM Klco, DH Spencer, CA Miller, M Griffith, TL Lamprecht, M O’Laughlin, ... Cancer cell 25 (3), 379-392, 2014 | 455 | 2014 |
| Immune escape of relapsed AML cells after allogeneic transplantation MJ Christopher, AA Petti, MP Rettig, CA Miller, E Chendamarai, ... New England Journal of Medicine 379 (24), 2330-2341, 2018 | 446 | 2018 |
| Key parameters of tumor epitope immunogenicity revealed through a consortium approach improve neoantigen prediction DK Wells, MM van Buuren, KK Dang, VM Hubbard-Lucey, KCF Sheehan, ... Cell 183 (3), 818-834. e13, 2020 | 422 | 2020 |
| Association between mutation clearance after induction therapy and outcomes in acute myeloid leukemia JM Klco, CA Miller, M Griffith, A Petti, DH Spencer, S Ketkar-Kulkarni, ... Jama 314 (8), 811-822, 2015 | 403 | 2015 |
TJ LeyProfessor of Medicine and Genetics, Washington University School of Medicine在 wustl.edu 的电子邮件经过验证