Synthetic protein scaffolds provide modular control over metabolic flux JE Dueber, GC Wu, GR Malmirchegini, TS Moon, CJ Petzold, AV Ullal, ... Nature biotechnology 27 (8), 753-759, 2009 | 1439 | 2009 |
Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds JG Zalatan, ME Lee, R Almeida, LA Gilbert, EH Whitehead, M La Russa, ... Cell 160 (1), 339-350, 2015 | 1120 | 2015 |
A highly characterized yeast toolkit for modular, multipart assembly ME Lee, WC DeLoache, B Cervantes, JE Dueber ACS synthetic biology 4 (9), 975-986, 2015 | 938 | 2015 |
BglBricks: A flexible standard for biological part assembly JC Anderson, JE Dueber, M Leguia, GC Wu, JA Goler, AP Arkin, ... Journal of biological engineering 4, 1-12, 2010 | 495 | 2010 |
An enzyme-coupled biosensor enables (S)-reticuline production in yeast from glucose WC DeLoache, ZN Russ, L Narcross, AM Gonzales, VJJ Martin, ... Nature chemical biology 11 (7), 465-471, 2015 | 429 | 2015 |
Selection of chromosomal DNA libraries using a multiplex CRISPR system OW Ryan, JM Skerker, MJ Maurer, X Li, JC Tsai, S Poddar, ME Lee, ... elife 3, e03703, 2014 | 421 | 2014 |
Reprogramming control of an allosteric signaling switch through modular recombination JE Dueber, BJ Yeh, K Chak, WA Lim Science 301 (5641), 1904-1908, 2003 | 417 | 2003 |
Use of modular, synthetic scaffolds for improved production of glucaric acid in engineered E. coli TS Moon, JE Dueber, E Shiue, KLJ Prather Metabolic engineering 12 (3), 298-305, 2010 | 342 | 2010 |
CRISPR-guided DNA polymerases enable diversification of all nucleotides in a tunable window SO Halperin, CJ Tou, EB Wong, C Modavi, DV Schaffer, JE Dueber Nature 560 (7717), 248-252, 2018 | 336 | 2018 |
DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency RJ Conrado, GC Wu, JT Boock, H Xu, SY Chen, T Lebar, J Turnšek, ... Nucleic acids research 40 (4), 1879-1889, 2012 | 313 | 2012 |
Spatial organization of enzymes for metabolic engineering H Lee, WC DeLoache, JE Dueber Metabolic engineering 14 (3), 242-251, 2012 | 304 | 2012 |
De novo design of bioactive protein switches RA Langan, SE Boyken, AH Ng, JA Samson, G Dods, AM Westbrook, ... Nature 572 (7768), 205-210, 2019 | 279 | 2019 |
Expression-level optimization of a multi-enzyme pathway in the absence of a high-throughput assay ME Lee, A Aswani, AS Han, CJ Tomlin, JE Dueber Nucleic acids research 41 (22), 10668-10678, 2013 | 269 | 2013 |
Employing a biochemical protecting group for a sustainable indigo dyeing strategy TM Hsu, DH Welner, ZN Russ, B Cervantes, RL Prathuri, PD Adams, ... Nature Chemical Biology 14 (3), 256-261, 2018 | 204 | 2018 |
Towards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways WC DeLoache, ZN Russ, JE Dueber Nature Communications 7 (1), 11152, 2016 | 178 | 2016 |
Engineering synthetic signaling proteins with ultrasensitive input/output control JE Dueber, EA Mirsky, WA Lim Nature biotechnology 25 (6), 660-662, 2007 | 168 | 2007 |
Rewiring cell signaling: the logic and plasticity of eukaryotic protein circuitry JE Dueber, BJ Yeh, RP Bhattacharyya, WA Lim Current opinion in structural biology 14 (6), 690-699, 2004 | 168 | 2004 |
A yeast platform for high-level synthesis of tetrahydroisoquinoline alkaloids ME Pyne, K Kevvai, PS Grewal, L Narcross, B Choi, L Bourgeois, ... Nature Communications 11 (1), 3337, 2020 | 147 | 2020 |
The pathogen protein EspFU hijacks actin polymerization using mimicry and multivalency NA Sallee, GM Rivera, JE Dueber, D Vasilescu, RD Mullins, BJ Mayer, ... Nature 454 (7207), 1005-1008, 2008 | 138 | 2008 |
Modular and tunable biological feedback control using a de novo protein switch AH Ng, TH Nguyen, M Gómez-Schiavon, G Dods, RA Langan, SE Boyken, ... Nature 572 (7768), 265-269, 2019 | 120 | 2019 |