| Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis N Singh, A Gurav, S Sivaprakasam, E Brady, R Padia, H Shi, ... Immunity 40 (1), 128-139, 2014 | 2244 | 2014 |
| The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition PV Chang, L Hao, S Offermanns, R Medzhitov Proceedings of the National Academy of Sciences 111 (6), 2247-2252, 2014 | 2052 | 2014 |
| Mammalian G proteins and their cell type specific functions N Wettschureck, S Offermanns Physiological reviews 85 (4), 1159-1204, 2005 | 1656 | 2005 |
| Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome L Macia, J Tan, AT Vieira, K Leach, D Stanley, S Luong, M Maruya, ... Nature communications 6 (1), 6734, 2015 | 1300 | 2015 |
| Activation of platelet function through G protein–coupled receptors S Offermanns Circulation research 99 (12), 1293-1304, 2006 | 1009 | 2006 |
| PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect S Tunaru, J Kero, A Schaub, C Wufka, A Blaukat, K Pfeffer, S Offermanns Nature medicine 9 (3), 352-355, 2003 | 927 | 2003 |
| The Concise Guide to PHARMACOLOGY 2019/20: G protein‐coupled receptors SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ... British journal of pharmacology 176, S21-S141, 2019 | 804 | 2019 |
| G12-G13–LARG–mediated signaling in vascular smooth muscle is required for salt-induced hypertension A Wirth, Z Benyó, M Lukasova, B Leutgeb, N Wettschureck, S Gorbey, ... Nature medicine 14 (1), 64-68, 2008 | 770 | 2008 |
| Defective platelet activation in Gαq-deficient mice S Offermanns, CF Toombs, YH Hu, MI Simon Nature 389 (6647), 183-186, 1997 | 749 | 1997 |
| (D)-β-hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G AKP Taggart, J Kero, X Gan, TQ Cai, K Cheng, M Ippolito, N Ren, ... Journal of Biological Chemistry 280 (29), 26649-26652, 2005 | 722 | 2005 |
| Gα15 and Gα16 couple a wide variety of receptors to phospholipase C (∗) S Offermanns, MI Simon Journal of Biological Chemistry 270 (25), 15175-15180, 1995 | 706 | 1995 |
| Platelet-derived nucleotides promote tumor-cell transendothelial migration and metastasis via P2Y2 receptor D Schumacher, B Strilic, KK Sivaraj, N Wettschureck, S Offermanns Cancer cell 24 (1), 130-137, 2013 | 671 | 2013 |
| G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets. S Offermanns, KL Laugwitz, K Spicher, G Schultz Proceedings of the National Academy of Sciences 91 (2), 504-508, 1994 | 629 | 1994 |
| Regeneration of fat cells from myofibroblasts during wound healing MV Plikus, CF Guerrero-Juarez, M Ito, YR Li, PH Dedhia, Y Zheng, ... Science 355 (6326), 748-752, 2017 | 589 | 2017 |
| Rho/Rho-kinase mediated signaling in physiology and pathophysiology N Wettschureck, S Offermanns Journal of molecular medicine 80, 629-638, 2002 | 585 | 2002 |
| ADP receptors of platelets and their inhibition C Gachet Thrombosis and haemostasis 86 (07), 222-232, 2001 | 583 | 2001 |
| GPR41/FFAR3 and GPR43/FFAR2 as cosensors for short-chain fatty acids in enteroendocrine cells vs FFAR3 in enteric neurons and FFAR2 in enteric leukocytes MK Nøhr, MH Pedersen, A Gille, KL Egerod, MS Engelstoft, AS Husted, ... Endocrinology 154 (10), 3552-3564, 2013 | 574 | 2013 |
| Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release SP Wang, R Chennupati, H Kaur, A Iring, N Wettschureck, S Offermanns The Journal of clinical investigation 126 (12), 4527-4536, 2016 | 557 | 2016 |
| Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis B Strilic, L Yang, J Albarrán-Juárez, L Wachsmuth, K Han, UC Müller, ... Nature 536 (7615), 215-218, 2016 | 534 | 2016 |
| Activation of G12/G13 Results in Shape Change and Rho/Rho-Kinase–mediated Myosin Light Chain Phosphorylation in Mouse Platelets B Klages, U Brandt, MI Simon, G Schultz, S Offermanns The Journal of cell biology 144 (4), 745-754, 1999 | 528 | 1999 |