Role for NLRP3 inflammasome–mediated, IL-1β–dependent responses in severe, steroid-resistant asthma RY Kim, JW Pinkerton, AT Essilfie, AAB Robertson, KJ Baines, AC Brown, ... American journal of respiratory and critical care medicine 196 (3), 283-297, 2017 | 418 | 2017 |
Interferon-ε protects the female reproductive tract from viral and bacterial infection KY Fung, NE Mangan, H Cumming, JC Horvat, JR Mayall, SA Stifter, ... Science 339 (6123), 1088-1092, 2013 | 274 | 2013 |
MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase–mediated suppression of histone deacetylase 2 RY Kim, JC Horvat, JW Pinkerton, MR Starkey, AT Essilfie, JR Mayall, ... Journal of Allergy and Clinical Immunology 139 (2), 519-532, 2017 | 218 | 2017 |
Macrolide therapy suppresses key features of experimental steroid-sensitive and steroid-insensitive asthma AT Essilfie, JC Horvat, RY Kim, JR Mayall, JW Pinkerton, EL Beckett, ... Thorax 70 (5), 458-467, 2015 | 146 | 2015 |
Mechanisms and treatments for severe, steroid‐resistant allergic airway disease and asthma PM Hansbro, RY Kim, MR Starkey, C Donovan, K Dua, JR Mayall, G Liu, ... Immunological reviews 278 (1), 41-62, 2017 | 142 | 2017 |
Role of iron in the pathogenesis of respiratory disease MK Ali, RY Kim, R Karim, JR Mayall, KL Martin, A Shahandeh, F Abbasian, ... The international journal of biochemistry & cell biology 88, 181-195, 2017 | 101 | 2017 |
Critical role for iron accumulation in the pathogenesis of fibrotic lung disease MK Ali, RY Kim, AC Brown, C Donovan, KS Vanka, JR Mayall, G Liu, ... The Journal of pathology 251 (1), 49-62, 2020 | 97 | 2020 |
Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma MK Ali, RY Kim, AC Brown, JR Mayall, R Karim, JW Pinkerton, G Liu, ... European Respiratory Journal 55 (4), 2020 | 62 | 2020 |
Relationship between type 2 cytokine and inflammasome responses in obesity-associated asthma JW Pinkerton, RY Kim, AC Brown, BE Rae, C Donovan, JR Mayall, ... Journal of Allergy and Clinical Immunology 149 (4), 1270-1280, 2022 | 46 | 2022 |
SARS-CoV-2 Spike protein promotes hyper-inflammatory response that can be ameliorated by Spike-antagonistic peptide and FDA-approved ER stress and MAP kinase inhibitors in vitro ACY Hsu, G Wang, AT Reid, PC Veerati, PS Pathinayake, K Daly, ... Biorxiv, 2020.09. 30.317818, 2020 | 42 | 2020 |
Defining the distinct, intrinsic properties of the novel type I interferon, IFNϵ SA Stifter, AY Matthews, NE Mangan, KY Fung, A Drew, MD Tate, ... Journal of Biological Chemistry 293 (9), 3168-3179, 2018 | 41 | 2018 |
T-helper 22 cells develop as a distinct lineage from Th17 cells during bacterial infection and phenotypic stability is regulated by T-bet JL Barnes, MW Plank, K Asquith, S Maltby, LR Sabino, GE Kaiko, ... Mucosal immunology 14 (5), 1077-1087, 2021 | 23 | 2021 |
Aim2 suppresses cigarette smoke‐induced neutrophil recruitment, neutrophil caspase‐1 activation and anti‐Ly6G‐mediated neutrophil depletion C Donovan, RY Kim, I Galvao, AG Jarnicki, AC Brown, B Jones‐Freeman, ... Immunology and Cell Biology 100 (4), 235-249, 2022 | 14 | 2022 |
Antiviral Responses of Tissue-resident CD49a+ Lung Natural Killer Cells Are Dysregulated in Chronic Obstructive Pulmonary Disease GE Cooper, J Mayall, C Donovan, TJ Haw, KF Budden, NG Hansbro, ... American Journal of Respiratory and Critical Care Medicine 207 (5), 553-565, 2023 | 12 | 2023 |
Chlamydia muridarum infection differentially alters smooth muscle function in mouse uterine horn and cervix JM Lee, JR Mayall, A Chevalier, H McCarthy, D Van Helden, PM Hansbro, ... American Journal of Physiology-Endocrinology and Metabolism 318 (6), E981-E994, 2020 | 10 | 2020 |
MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying PI3K-mediated suppression of HDAC2 RY Kim, JC Horvat, JW Pinkerton, MR Starkey, AT Essilfie, JR Mayall, ... J. Allergy Clin. Immunol, 2016 | 9 | 2016 |
Interferon-epsilon is a novel regulator of NK cell responses in the uterus JR Mayall, JC Horvat, NE Mangan, A Chevalier, H McCarthy, D Hampsey, ... EMBO molecular medicine 16 (2), 267-293, 2024 | 5 | 2024 |
Characterization and inhibition of inflammasome responses in severe and non-severe asthma JC Horvat, RY Kim, N Weaver, C Augood, AC Brown, C Donovan, ... Respiratory research 24 (1), 303, 2023 | 5 | 2023 |
Landscape fire smoke airway exposure impairs respiratory and cardiac function and worsens experimental asthma HM Gomez, TJ Haw, D Ilic, P Robinson, C Donovan, AJ Croft, KS Vanka, ... Journal of Allergy and Clinical Immunology, 2024 | 3 | 2024 |
IL-5/IL-13 drive NLRP3 inflammasome-mediated, steroid-resistant AHR in a model of obesity-associated asthma J Pinkerton, R Kim, A Brown, B Rae, J Mayall, MK Ali, M Starkey, ... European Respiratory Journal 54 (suppl 63), 2019 | 3 | 2019 |