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Lauren J. Rajakovich
Lauren J. Rajakovich
在 uw.edu 的电子邮件经过验证 - 首页
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引用次数
引用次数
年份
Two distinct mechanisms for C–C desaturation by iron (II)-and 2-(oxo) glutarate-dependent oxygenases: Importance of α-heteroatom assistance
NP Dunham, W Chang, AJ Mitchell, RJ Martinie, B Zhang, JA Bergman, ...
Journal of the American Chemical Society 140 (23), 7116-7126, 2018
1142018
Metabolic functions of the human gut microbiota: the role of metalloenzymes
LJ Rajakovich, EP Balskus
Natural product reports 36 (4), 593-625, 2019
952019
Substrate-triggered addition of dioxygen to the diferrous cofactor of aldehyde-deformylating oxygenase to form a diferric-peroxide intermediate
ME Pandelia, N Li, H Nørgaard, DM Warui, LJ Rajakovich, W Chang, ...
Journal of the American Chemical Society 135 (42), 15801-15812, 2013
852013
Rapid reduction of the diferric-peroxyhemiacetal intermediate in aldehyde-deformylating oxygenase by a cyanobacterial ferredoxin: Evidence for a free-radical mechanism
LJ Rajakovich, H Nørgaard, DM Warui, W Chang, N Li, SJ Booker, ...
Journal of the American Chemical Society 137 (36), 11695-11709, 2015
652015
Substrate-triggered Formation of a Peroxo-Fe2 (III/III) Intermediate during Fatty Acid Decarboxylation by UndA
B Zhang, LJ Rajakovich, D Van Cura, EJ Blaesi, AJ Mitchell, CR Tysoe, ...
Journal of the American Chemical Society 141 (37), 14510–14514, 2019
572019
Elucidation of an anaerobic pathway for metabolism of L-carnitine-derived γ-butyrobetaine to trimethylamine in human gut bacteria
LJ Rajakovich, B Fu, M Bollenbach, EP Balskus
Proceedings of the National Academy of Sciences 118 (32), e2101498118, 2021
532021
Structural Basis for Superoxide Activation of Flavobacterium johnsoniae Class I Ribonucleotide Reductase and for Radical Initiation by Its Dimanganese Cofactor
HR Rose, MK Ghosh, AO Maggiolo, CJ Pollock, EJ Blaesi, V Hajj, Y Wei, ...
Biochemistry 57 (18), 2679-2693, 2018
532018
Functional analysis of Bacillus subtilis genes involved in the biosynthesis of 4-thiouridine in tRNA
LJ Rajakovich, J Tomlinson, PC Dos Santos
Journal of bacteriology 194 (18), 4933-4940, 2012
522012
Efficient Delivery of Long-Chain Fatty Aldehydes from the Nostoc punctiforme Acyl–Acyl Carrier Protein Reductase to Its Cognate Aldehyde-Deformylating Oxygenase
DM Warui, ME Pandelia, LJ Rajakovich, C Krebs, JM Bollinger Jr, ...
Biochemistry 54 (4), 1006-1015, 2015
472015
Hydrogen donation but not abstraction by a tyrosine (Y68) during endoperoxide installation by verruculogen synthase (FtmOx1)
NP Dunham, JM Del Río Pantoja, B Zhang, LJ Rajakovich, BD Allen, ...
Journal of the American Chemical Society 141 (25), 9964-9979, 2019
442019
A new microbial pathway for organophosphonate degradation catalyzed by two previously misannotated non-heme-iron oxygenases
LJ Rajakovich, ME Pandelia, AJ Mitchell, W Chang, B Zhang, AK Boal, ...
Biochemistry 58 (12), 1627-1647, 2019
422019
O–H activation by an unexpected ferryl intermediate during catalysis by 2-hydroxyethylphosphonate dioxygenase
SC Peck, C Wang, LMK Dassama, B Zhang, Y Guo, LJ Rajakovich, ...
Journal of the American Chemical Society 139 (5), 2045-2052, 2017
382017
Emerging structural and functional diversity in proteins with dioxygen-reactive dinuclear transition metal cofactors
LJ Rajakovich, B Zhang, MJ McBride, AK Boal, C Krebs, JM Bollinger Jr
Comprehensive Natural Products III, 3rd Edition: Chemistry & Biology, 215-250, 2020
232020
Molecular basis for enantioselective herbicide degradation imparted by aryloxyalkanoate dioxygenases in transgenic plants
JR Chekan, C Ongpipattanakul, TR Wright, B Zhang, JM Bollinger Jr, ...
Proceedings of the National Academy of Sciences 116 (27), 13299-13304, 2019
202019
Mechanism of the Multistep Catalytic Cycle of 6-Hydroxynicotinate 3-Monooxygenase Revealed by Global Kinetic Analysis
SW Perkins, MZ Hlaing, KA Hicks, LJ Rajakovich, MJ Snider
Biochemistry 62 (10), 1553-1567, 2023
32023
Iron-sulfur cluster-dependent enzymes and molybdenum-dependent reductases in the anaerobic metabolism of human gut microbes
LE Zahn, PM Gannon, LJ Rajakovich
Metallomics, mfae049, 2024
22024
Exploring the functional and mechanistic diversity of diiron oxidases and oxygenases
LJ Rajakovich
The Pennsylvania State University, 2017
22017
Long chain acyl-CoA dehydrogenase deficiency: a new inborn error of metabolism manifesting as congenital surfactant deficiency
KR Suhrie, L Rajakovich, AW Mohsen, J Vockley
MOLECULAR GENETICS AND METABOLISM 102 (3), 251-252, 2011
12011
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