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L1 drives IFN in senescent cells and promotes age-associated inflammation M De Cecco, T Ito, AP Petrashen, AE Elias, NJ Skvir, SW Criscione, ... Nature 566 (7742), 73-78, 2019 | 976 | 2019 |
SIRT6 promotes DNA repair under stress by activating PARP1 Z Mao, C Hine, X Tian, M Van Meter, M Au, A Vaidya, A Seluanov, ... Science 332 (6036), 1443-1446, 2011 | 948 | 2011 |
High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat X Tian, J Azpurua, C Hine, A Vaidya, M Myakishev-Rempel, J Ablaeva, ... Nature 499 (7458), 346-349, 2013 | 935 | 2013 |
Comparison of nonhomologous end joining and homologous recombination in human cells Z Mao, M Bozzella, A Seluanov, V Gorbunova DNA repair 7 (10), 1765-1771, 2008 | 887 | 2008 |
DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells Z Mao, M Bozzella, A Seluanov, V Gorbunova Cell cycle 7 (18), 2902-2906, 2008 | 841 | 2008 |
Hypersensitivity to contact inhibition provides a clue to cancer resistance of naked mole-rat A Seluanov, C Hine, J Azpurua, M Feigenson, M Bozzella, Z Mao, ... Proceedings of the National Academy of Sciences 106 (46), 19352-19357, 2009 | 481 | 2009 |
Changes in DNA repair during aging V Gorbunova, A Seluanov, Z Mao, C Hine Nucleic acids research 35 (22), 7466-7474, 2007 | 454 | 2007 |
SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age M Van Meter, M Kashyap, S Rezazadeh, AJ Geneva, TD Morello, ... Nature communications 5 (1), 5011, 2014 | 437 | 2014 |
LINE1 derepression in aged wild-type and SIRT6-deficient mice drives inflammation M Simon, M Van Meter, J Ablaeva, Z Ke, RS Gonzalez, T Taguchi, ... Cell metabolism 29 (4), 871-885. e5, 2019 | 397 | 2019 |
Establishing primary adult fibroblast cultures from rodents A Seluanov, A Vaidya, V Gorbunova Journal of visualized experiments: JoVE, 2033, 2010 | 370 | 2010 |
Non-homologous DNA end joining in plant cells is associated with deletions and filler DNA insertions V Gorbunova, AA Levy Nucleic acids research 25 (22), 4650-4657, 1997 | 350 | 1997 |
Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis V Gorbunova, A Seluanov, OM Pereira-Smith Journal of Biological Chemistry 277 (41), 38540-38549, 2002 | 333 | 2002 |
DNA end joining becomes less efficient and more error-prone during cellular senescence A Seluanov, D Mittelman, OM Pereira-Smith, JH Wilson, V Gorbunova Proceedings of the National Academy of Sciences 101 (20), 7624-7629, 2004 | 316 | 2004 |
Mechanisms of cancer resistance in long-lived mammals A Seluanov, VN Gladyshev, J Vijg, V Gorbunova Nature Reviews Cancer 18 (7), 433-441, 2018 | 296 | 2018 |
ATRX loss promotes tumor growth and impairs nonhomologous end joining DNA repair in glioma C Koschmann, AA Calinescu, FJ Nunez, A Mackay, J Fazal-Salom, ... Science translational medicine 8 (328), 328ra28-328ra28, 2016 | 293 | 2016 |
SIRT6 is responsible for more efficient DNA double-strand break repair in long-lived species X Tian, D Firsanov, Z Zhang, Y Cheng, L Luo, G Tombline, R Tan, ... Cell 177 (3), 622-638. e22, 2019 | 291 | 2019 |
How plants make ends meet: DNA double-strand break repair V Gorbunova, AA Levy Trends in plant science 4 (7), 263-269, 1999 | 273 | 1999 |
Telomerase activity coevolves with body mass not lifespan A Seluanov, Z Chen, C Hine, THC Sasahara, AACM Ribeiro, KC Catania, ... Aging cell 6 (1), 45-52, 2007 | 268 | 2007 |
The role of retrotransposable elements in ageing and age-associated diseases V Gorbunova, A Seluanov, P Mita, W McKerrow, D Fenyö, JD Boeke, ... Nature 596 (7870), 43-53, 2021 | 263 | 2021 |