Cytotoxic and anticancer activities of isatin and its derivatives: a comprehensive review from 2000-2008 KL Vine, L Matesic, JM Locke, M Ranson, D Skropeta Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2009 | 360 | 2009 |
In vitro cytotoxicity evaluation of some substituted isatin derivatives KL Vine, JM Locke, M Ranson, SG Pyne, JB Bremner Bioorganic & medicinal chemistry 15 (2), 931-938, 2007 | 278 | 2007 |
Towards clinical translation of ligand-functionalized liposomes in targeted cancer therapy: Challenges and opportunities L Belfiore, DN Saunders, M Ranson, KJ Thurecht, G Storm, KL Vine Journal of controlled release 277, 1-13, 2018 | 275 | 2018 |
Biopolymers for antitumor implantable drug delivery systems: recent advances and future outlook S Talebian, J Foroughi, SJ Wade, KL Vine, A Dolatshahi‐Pirouz, ... Advanced Materials 30 (31), 1706665, 2018 | 199 | 2018 |
An investigation into the cytotoxicity and mode of action of some novel N-alkyl-substituted isatins KL Vine, JM Locke, M Ranson, SG Pyne, JB Bremner Journal of medicinal chemistry 50 (21), 5109-5117, 2007 | 199 | 2007 |
Gastric cancer stem cells: evidence, potential markers, and clinical implications D Brungs, M Aghmesheh, KL Vine, TM Becker, MG Carolan, M Ranson Journal of gastroenterology 51, 313-326, 2016 | 148 | 2016 |
N-phenethyl and N-naphthylmethyl isatins and analogues as in vitro cytotoxic agents L Matesic, JM Locke, JB Bremner, SG Pyne, D Skropeta, M Ranson, ... Bioorganic & medicinal chemistry 16 (6), 3118-3124, 2008 | 121 | 2008 |
SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation R Zeineddine, JF Pundavela, L Corcoran, EM Stewart, D Do-Ha, M Bax, ... Molecular neurodegeneration 10, 1-18, 2015 | 93 | 2015 |
SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer NLE Harris, C Vennin, JRW Conway, KL Vine, M Pinese, MJ Cowley, ... Oncogene 36 (30), 4288-4298, 2017 | 92 | 2017 |
Recent highlights in the development of isatin-based anticancer agents KL Vine, L Matesic, JM Locke, D Skropeta Adv. Anticancer Agents Med. Chem 2, 254-312, 2013 | 88 | 2013 |
Synthesis and anti-leukaemic activity of pyrrolo [3, 2, 1-hi] indole-1, 2-diones, pyrrolo [3, 2, 1-ij] quinoline-1, 2-diones and other polycyclic isatin derivatives L Matesic, JM Locke, KL Vine, M Ranson, JB Bremner, D Skropeta Tetrahedron 68 (34), 6810-6819, 2012 | 70 | 2012 |
Improving the delivery of SOD1 antisense oligonucleotides to motor neurons using calcium phosphate-lipid nanoparticles L Chen, C Watson, M Morsch, NJ Cole, RS Chung, DN Saunders, ... Frontiers in neuroscience 11, 476, 2017 | 66 | 2017 |
The urokinase plasminogen activation system in gastroesophageal cancer: A systematic review and meta-analysis D Brungs, J Chen, M Aghmesheh, KL Vine, TM Becker, MG Carolan, ... Oncotarget 8 (14), 23099, 2017 | 59 | 2017 |
Translationally controlled tumour protein TCTP is induced early in human colorectal tumours and contributes to the resistance of HCT116 colon cancer cells to 5-FU and oxaliplatin UA Bommer, KL Vine, P Puri, M Engel, L Belfiore, K Fildes, M Batterham, ... Cell Communication and Signaling 15, 1-15, 2017 | 55 | 2017 |
Non-viral vector-mediated gene therapy for ALS: challenges and future perspectives GR Ediriweera, L Chen, JJ Yerbury, KJ Thurecht, KL Vine Molecular Pharmaceutics 18 (6), 2142-2160, 2021 | 50 | 2021 |
SOD1A4V aggregation alters ubiquitin homeostasis in a cell model of ALS NE Farrawell, I Lambert-Smith, K Mitchell, J McKenna, L McAlary, ... Journal of Cell Science 131 (11), jcs209122, 2018 | 48 | 2018 |
Establishment of novel long-term cultures from EpCAM positive and negative circulating tumour cells from patients with metastatic gastroesophageal cancer D Brungs, E Minaei, AK Piper, J Perry, A Splitt, M Carolan, S Ryan, XJ Wu, ... Scientific reports 10 (1), 539, 2020 | 43 | 2020 |
Probing the pharmacokinetics of cucurbit [7, 8 and 10] uril: and a dinuclear ruthenium antimicrobial complex encapsulated in cucurbit [10] uril F Li, AK Gorle, M Ranson, KL Vine, R Kinobe, M Feterl, JM Warner, ... Organic & Biomolecular Chemistry 15 (19), 4172-4179, 2017 | 41 | 2017 |
Quantification of ligand density and stoichiometry on the surface of liposomes using single-molecule fluorescence imaging L Belfiore, LM Spenkelink, M Ranson, AM van Oijen, KL Vine Journal of Controlled Release 278, 80-86, 2018 | 39 | 2018 |
Ubiquitin homeostasis is disrupted in TDP-43 and FUS cell models of ALS NE Farrawell, L McAlary, JS Lum, CG Chisholm, ST Warraich, IP Blair, ... Iscience 23 (11), 2020 | 37 | 2020 |