| Human senataxin resolves RNA/DNA hybrids formed at transcriptional pause sites to promote Xrn2-dependent termination K Skourti-Stathaki, NJ Proudfoot, N Gromak Molecular cell 42 (6), 794-805, 2011 | 903 | 2011 |
| Human 5′→ 3′ exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites S West, N Gromak, NJ Proudfoot Nature 432 (7016), 522-525, 2004 | 637 | 2004 |
| Primary microRNA transcripts are processed co-transcriptionally M Morlando, M Ballarino, N Gromak, F Pagano, I Bozzoni, NJ Proudfoot Nature structural & molecular biology 15 (9), 902-909, 2008 | 525 | 2008 |
| Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing CJ Webby, A Wolf, N Gromak, M Dreger, H Kramer, B Kessler, ML Nielsen, ... Science 325 (5936), 90-93, 2009 | 474 | 2009 |
| RNA/DNA hybrid interactome identifies DXH9 as a molecular player in transcriptional termination and R-loop-associated DNA damage A Cristini, M Groh, MS Kristiansen, N Gromak Cell reports 23 (6), 1891-1905, 2018 | 394 | 2018 |
| R-loops associated with triplet repeat expansions promote gene silencing in Friedreich ataxia and fragile X syndrome M Groh, MMP Lufino, R Wade-Martins, N Gromak PLoS genetics 10 (5), e1004318, 2014 | 386 | 2014 |
| Increased global transcription activity as a mechanism of replication stress in cancer P Kotsantis, LM Silva, S Irmscher, RM Jones, L Folkes, N Gromak, ... Nature communications 7 (1), 13087, 2016 | 339 | 2016 |
| Pause sites promote transcriptional termination of mammalian RNA polymerase II N Gromak, S West, NJ Proudfoot Molecular and cellular biology 26 (10), 3986-3996, 2006 | 253 | 2006 |
| Out of balance: R-loops in human disease M Groh, N Gromak PLoS genetics 10 (9), e1004630, 2014 | 220 | 2014 |
| N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells A Abakir, TC Giles, A Cristini, JM Foster, N Dai, M Starczak, ... Nature genetics 52 (1), 48-55, 2020 | 207 | 2020 |
| Exon tethering in transcription by RNA polymerase II MJ Dye, N Gromak, NJ Proudfoot Molecular cell 21 (6), 849-859, 2006 | 174 | 2006 |
| Dual processing of R-loops and topoisomerase I induces transcription-dependent DNA double-strand breaks A Cristini, G Ricci, S Britton, S Salimbeni, SN Huang, J Marinello, ... Cell reports 28 (12), 3167-3181. e6, 2019 | 150 | 2019 |
| Antagonistic regulation of α-actinin alternative splicing by CELF proteins and polypyrimidine tract binding protein N Gromak, AJ Matlin, TA Cooper, CWJ Smith Rna 9 (4), 443-456, 2003 | 148 | 2003 |
| Senataxin: genome guardian at the interface of transcription and neurodegeneration M Groh, LO Albulescu, A Cristini, N Gromak Journal of molecular biology 429 (21), 3181-3195, 2017 | 143 | 2017 |
| The PTB interacting protein raver1 regulates α‐tropomyosin alternative splicing N Gromak, A Rideau, J Southby, ADJ Scadden, C Gooding, S Hüttelmaier, ... The EMBO journal, 2003 | 136 | 2003 |
| Adenylation and exosome-mediated degradation of cotranscriptionally cleaved pre-messenger RNA in human cells S West, N Gromak, CJ Norbury, NJ Proudfoot Molecular cell 21 (3), 437-443, 2006 | 126 | 2006 |
| Drosha regulates gene expression independently of RNA cleavage function N Gromak, M Dienstbier, S Macias, M Plass, E Eyras, JF Caceres, ... Cell reports 5 (6), 1499-1510, 2013 | 90 | 2013 |
| DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes AMS Giordano, M Luciani, F Gatto, M Abou Alezz, C Beghè, L Della Volpe, ... Journal of Experimental Medicine 219 (4), e20211121, 2022 | 64 | 2022 |
| RNase H2, mutated in Aicardi‐Goutières syndrome, resolves co-transcriptional R-loops to prevent DNA breaks and inflammation A Cristini, M Tellier, F Constantinescu, C Accalai, LO Albulescu, ... Nature communications 13 (1), 2961, 2022 | 62 | 2022 |
| Intronic microRNAs: a crossroad in gene regulation N Gromak Biochemical Society Transactions 40 (4), 759-761, 2012 | 51 | 2012 |
