In vitro and in vivo evaluation of ruthenium (II)− arene PTA complexes C Scolaro, A Bergamo, L Brescacin, R Delfino, M Cocchietto, G Laurenczy, ... Journal of medicinal chemistry 48 (12), 4161-4171, 2005 | 993 | 2005 |
Approaching tumour therapy beyond platinum drugs: status of the art and perspectives of ruthenium drug candidates A Bergamo, C Gaiddon, JHM Schellens, JH Beijnen, G Sava Journal of inorganic biochemistry 106 (1), 90-99, 2012 | 642 | 2012 |
Ruthenium antimetastatic agents E Alessio, G Mestroni, A Bergamo, G Sava Current Topics in Medicinal Chemistry 4 (15), 1525-1535, 2004 | 622 | 2004 |
Metal-based antitumour drugs in the post genomic era PJ Dyson, G Sava Dalton Transactions, 1929-1933, 2006 | 604 | 2006 |
A review on usnic acid, an interesting natural compound M Cocchietto, N Skert, P Nimis, G Sava Naturwissenschaften 89, 137-146, 2002 | 541 | 2002 |
Ruthenium anticancer compounds: myths and realities of the emerging metal-based drugs A Bergamo, G Sava Dalton Transactions 40 (31), 7817-7823, 2011 | 518 | 2011 |
Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy S Leijen, SA Burgers, P Baas, D Pluim, M Tibben, E van Werkhoven, ... Investigational new drugs 33, 201-214, 2015 | 498 | 2015 |
Cis-and trans-dihalotetrakis (dimethyl sulfoxide) ruthenium (II) complexes (RuX2 (DMSO) 4; X= Cl, Br): synthesis, structure, and antitumor activity E Alessio, G Mestroni, G Nardin, WM Attia, M Calligaris, G Sava, S Zorzet Inorganic chemistry 27 (23), 4099-4106, 1988 | 458 | 1988 |
Organometallic ruthenium-based antitumor compounds with novel modes of action WH Ang, A Casini, G Sava, PJ Dyson Journal of Organometallic Chemistry 696 (5), 989-998, 2011 | 433 | 2011 |
Dual action of NAMI-A in inhibition of solid tumor metastasis: selective targeting of metastatic cells and binding to collagen G Sava, S Zorzet, C Turrin, F Vita, MR Soranzo, G Zabucchi, M Cocchietto, ... Clinical Cancer Research 9 (5), 1898-1905, 2003 | 371 | 2003 |
Influence of chemical stability on the activity of the antimetastasis ruthenium compound NAMI-A G Sava, A Bergamo, S Zorzet, B Gava, C Casarsa, M Cocchietto, A Furlani, ... European Journal of Cancer 38 (3), 427-435, 2002 | 310 | 2002 |
Modulation of the metastatic progression of breast cancer with an organometallic ruthenium compound A Bergamo, A Masi, PJ Dyson, G Sava International Journal of Oncology 33 (6), 1281-1289, 2008 | 292 | 2008 |
Ruthenium complexes can target determinants of tumour malignancy A Bergamo, G Sava Dalton Transactions, 1267-1272, 2007 | 282 | 2007 |
Metal-based antitumour drugs in the post-genomic era: what comes next? G Sava, A Bergamo, PJ Dyson Dalton Transactions 40 (36), 9069-9075, 2011 | 279 | 2011 |
In vitro cell cycle arrest, in vivo action on solid metastasizing tumors, and host toxicity of the antimetastatic drug NAMI-A and cisplatin A Bergamo, R Gagliardi, V Scarcia, A Furlani, E Alessio, G Mestroni, ... Journal of Pharmacology and Experimental Therapeutics 289 (1), 559-564, 1999 | 273 | 1999 |
Pharmacological control of lung metastases of solid tumours by a novel ruthenium complex G Sava, I Capozzi, K Clerici, G Gagliardi, E Alessio, G Mestroni Clinical & experimental metastasis 16, 371-379, 1998 | 267 | 1998 |
Linking the future of anticancer metal-complexes to the therapy of tumour metastases A Bergamo, G Sava Chemical Society Reviews 44 (24), 8818-8835, 2015 | 246 | 2015 |
Development of ruthenium antitumor drugs that overcome multidrug resistance mechanisms CA Vock, WH Ang, C Scolaro, AD Phillips, L Lagopoulos, ... Journal of medicinal chemistry 50 (9), 2166-2175, 2007 | 234 | 2007 |
In vivo tumour and metastasis reduction and in vitro effects on invasion assays of the ruthenium RM175 and osmium AFAP51 organometallics in the mammary cancer model A Bergamo, A Masi, AFA Peacock, A Habtemariam, PJ Sadler, G Sava Journal of inorganic biochemistry 104 (1), 79-86, 2010 | 233 | 2010 |
The hydrolysis of the anti-cancer ruthenium complex NAMI-A affects its DNA binding and antimetastatic activity: an NMR evaluation M Bacac, ACG Hotze, K van der Schilden, JG Haasnoot, S Pacor, ... Journal of inorganic biochemistry 98 (2), 402-412, 2004 | 221 | 2004 |