| Three-dimensional structure of a genetically engineered variant of porcine growth hormone. SS Abdel-Meguid, HS Shieh, WW Smith, HE Dayringer, BN Violand, ... Proceedings of the National Academy of Sciences 84 (18), 6434-6437, 1987 | 738 | 1987 |
| Structural basis of inhibitor selectivity in MAP kinases Z Wang, BJ Canagarajah, JC Boehm, S Kassisà, MH Cobb, PR Young, ... Structure 6 (9), 1117-1128, 1998 | 547 | 1998 |
| Structure of southern bean mosaic virus at 2.8 Å resolution C Abad-Zapatero, SS Abdel-Meguid, JE Johnson, AGW Leslie, I Rayment, ... Nature 286 (5768), 33-39, 1980 | 546 | 1980 |
| Crystal Structure of the IMP-1 Metallo β-Lactamase from Pseudomonas aeruginosa and Its Complex with a Mercaptocarboxylate Inhibitor: Binding Determinants of a Potent … NO Concha, CA Janson, P Rowling, S Pearson, CA Cheever, BP Clarke, ... Biochemistry 39 (15), 4288-4298, 2000 | 388 | 2000 |
| Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality D Lee, SA Long, JL Adams, G Chan, KS Vaidya, TA Francis, K Kikly, ... Journal of Biological Chemistry 275 (21), 16007-16014, 2000 | 325 | 2000 |
| Structure and topological symmetry of the glyphosate target 5-enolpyruvylshikimate-3-phosphate synthase: a distinctive protein fold. WC Stallings, SS Abdel-Meguid, LW Lim, HS Shieh, HE Dayringer, ... Proceedings of the National Academy of Sciences 88 (11), 5046-5050, 1991 | 228 | 1991 |
| Processing and post-refinement of oscillation camera data MG Rossmann, AGW Leslie, SS Abdel-Meguid, T Tsukihara Journal of Applied Crystallography 12 (6), 570-581, 1979 | 221 | 1979 |
| Cloning, expression, and initial characterization of a novel cytokine-like gene family Y Zhu, G Xu, A Patel, MM McLaughlin, C Silverman, KA Knecht, ... Genomics 80 (2), 144-150, 2002 | 212 | 2002 |
| Crystal structure of β-ketoacyl-acyl carrier protein synthase III: a key condensing enzyme in bacterial fatty acid biosynthesis X Qiu, CA Janson, AK Konstantinidis, S Nwagwu, C Silverman, WW Smith, ... Journal of Biological Chemistry 274 (51), 36465-36471, 1999 | 202 | 1999 |
| Unique fold and active site in cytomegalovirus protease X Qiu, JS Culp, AG DiLella, B Hellmig, SS Hoog, CA Janson, WW Smith, ... Nature 383 (6597), 275-279, 1996 | 200 | 1996 |
| Binding Interactions of Human Interleukin 5 with Its Receptor α Subunit: LARGE SCALE PRODUCTION, STRUCTURAL, AND FUNCTIONAL STUDIES OF DROSOPHILA-EXPRESSED RECOMBINANT PROTEINS (∗) K Johanson, E Appelbaum, M Doyle, P Hensley, B Zhao, ... Journal of Biological Chemistry 270 (16), 9459-9471, 1995 | 199 | 1995 |
| Design of potent and selective human cathepsin K inhibitors that span the active site SK Thompson, SM Halbert, MJ Bossard, TA Tomaszek, MA Levy, B Zhao, ... Proceedings of the National Academy of Sciences 94 (26), 14249-14254, 1997 | 184 | 1997 |
| Crystal structure of human osteoclast cathepsin K complex with E-64 B Zhao, CA Janson, BY Amegadzie, K D'Alessio, C Griffin, CR Hanning, ... Nature structural biology 4 (2), 109-111, 1997 | 155 | 1997 |
| Cleavage of the site-specific recombination protein gamma delta resolvase: the smaller of two fragments binds DNA specifically. SS Abdel-Meguid, ND Grindley, NS Templeton, TA Steitz Proceedings of the National Academy of Sciences 81 (7), 2001-2005, 1984 | 139 | 1984 |
| Structure and design of potent and selective cathepsin K inhibitors DS Yamashita, WW Smith, B Zhao, CA Janson, TA Tomaszek, ... Journal of the American Chemical Society 119 (46), 11351-11352, 1997 | 119 | 1997 |
| Inhibition of human immunodeficiency virus-1 protease by a C2-symmetric phosphinate. Synthesis and crystallographic analysis SS Abdel-Meguid, B Zhao, KHM Murthy, E Winborne, JK Choi, ... Biochemistry 32 (31), 7972-7980, 1993 | 119 | 1993 |
| Cholesterol: the good, the bad, and the ugly-therapeutic targets for the treatment of dyslipidemia NA Elshourbagy, HV Meyers, SS Abdel-Meguid Medical Principles and Practice 23 (2), 99-111, 2014 | 109 | 2014 |
| An orally bioavailable HIV-1 protease inhibitor containing an imidazole-derived peptide bond replacement: crystallographic and pharmacokinetic analysis SS Abdel-Meguid, BW Metcalf, TJ Carr, P Demarsh, RL DesJarlais, ... Biochemistry 33 (39), 11671-11677, 1994 | 100 | 1994 |
| Use of Papain as a Model for the Structure-Based Design of Cathepsin K Inhibitors: Crystal Structures of Two Papain− Inhibitor Complexes Demonstrate Binding to S ‘-Subsites JM LaLonde, B Zhao, WW Smith, CA Janson, RL DesJarlais, ... Journal of medicinal chemistry 41 (23), 4567-4576, 1998 | 98 | 1998 |
| Compounds and methods for treatment of thrombosis SS Abdel-Meguid, RE Babine, H Deng, L Jin, J Lin, SR Magee, ... US Patent 7,217,794, 2007 | 90 | 2007 |