| Molecular mechanisms underlying nonribosomal peptide synthesis: approaches to new antibiotics SA Sieber, MA Marahiel Chemical reviews 105 (2), 715-738, 2005 | 765 | 2005 |
| Chemical proteomics approaches for identifying the cellular targets of natural products MH Wright, SA Sieber Natural product reports 33 (5), 681-708, 2016 | 423 | 2016 |
| The microstructure and micromechanics of the tendon–bone insertion L Rossetti, LA Kuntz, E Kunold, J Schock, KW Müller, H Grabmayr, ... Nature materials 16 (6), 664-670, 2017 | 330 | 2017 |
| Proteomic profiling of metalloprotease activities with cocktails of active-site probes SA Sieber, S Niessen, HS Hoover, BF Cravatt Nature chemical biology 2 (5), 274-281, 2006 | 322 | 2006 |
| Electrophilic natural products and their biological targets M Gersch, J Kreuzer, SA Sieber Natural product reports 29 (6), 659-682, 2012 | 312 | 2012 |
| Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs A Javaheri, T Kruse, K Moonens, R Mejías-Luque, A Debraekeleer, ... Nature microbiology 2 (1), 1-13, 2016 | 272 | 2016 |
| β-Lactones as Specific Inhibitors of ClpP Attenuate the Production of Extracellular Virulence Factors of Staphylococcus aureus T Böttcher, SA Sieber Journal of the American Chemical Society 130 (44), 14400-14401, 2008 | 235 | 2008 |
| Substrate transfer from the chaperone Hsp70 to Hsp90 H Wegele, SK Wandinger, AB Schmid, J Reinstein, J Buchner Journal of molecular biology 356 (3), 802-811, 2006 | 228 | 2006 |
| Natural products and their biological targets: proteomic and metabolomic labeling strategies T Böttcher, M Pitscheider, SA Sieber Angewandte Chemie International Edition 49 (15), 2680-2698, 2010 | 223 | 2010 |
| β‐lactones as privileged structures for the active‐site labeling of versatile bacterial enzyme classes T Böttcher, SA Sieber Angewandte Chemie International Edition 47 (24), 4600-4603, 2008 | 200 | 2008 |
| Learning from Nature's Drug Factories: Nonribosomal Synthesisof MacrocyclicPeptides SA Sieber, MA Marahiel Journal of bacteriology 185 (24), 7036-7043, 2003 | 198 | 2003 |
| Thinking outside the box—novel antibacterials to tackle the resistance crisis M Lakemeyer, W Zhao, FA Mandl, P Hammann, SA Sieber Angewandte Chemie International Edition 57 (44), 14440-14475, 2018 | 169 | 2018 |
| Synthesis and derivatization of daptomycin: a chemoenzymatic route to acidic lipopeptide antibiotics J Grünewald, SA Sieber, C Mahlert, U Linne, MA Marahiel Journal of the American Chemical Society 126 (51), 17025-17031, 2004 | 169 | 2004 |
| Characterization of the surfactin synthetase C-terminal thioesterase domain as a cyclic depsipeptide synthase CC Tseng, SD Bruner, RM Kohli, MA Marahiel, CT Walsh, SA Sieber Biochemistry 41 (45), 13350-13359, 2002 | 167 | 2002 |
| β-Lactams as selective chemical probes for the in vivo labeling of bacterial enzymes involved in cell wall biosynthesis, antibiotic resistance, and virulence I Staub, SA Sieber Journal of the American Chemical Society 130 (40), 13400-13409, 2008 | 152 | 2008 |
| AAA+ chaperones and acyldepsipeptides activate the ClpP protease via conformational control M Gersch, K Famulla, M Dahmen, C Göbl, I Malik, K Richter, VS Korotkov, ... Nature communications 6 (1), 6320, 2015 | 142 | 2015 |
| Identification of acyl protein thioesterases 1 and 2 as the cellular targets of the Ras‐signaling modulators palmostatin B and M M Rusch, TJ Zimmermann, M Bürger, FJ Dekker, K Görmer, G Triola, ... Angewandte Chemie-International Edition 50 (42), 9838, 2011 | 140 | 2011 |
| Unraveling the protein targets of vancomycin in living S. aureus and E. faecalis cells J Eirich, R Orth, SA Sieber Journal of the American Chemical Society 133 (31), 12144-12153, 2011 | 126 | 2011 |
| Chirality of peptide bond-forming condensation domains in nonribosomal peptide synthetases: the C5 domain of tyrocidine synthetase is a DCL catalyst SL Clugston, SA Sieber, MA Marahiel, CT Walsh Biochemistry 42 (41), 12095-12104, 2003 | 125 | 2003 |
| A whole proteome inventory of background photocrosslinker binding P Kleiner, W Heydenreuter, M Stahl, VS Korotkov, SA Sieber Angewandte Chemie International Edition 56 (5), 1396-1401, 2017 | 124 | 2017 |