| CasX enzymes comprise a distinct family of RNA-guided genome editors JJ Liu, N Orlova, BL Oakes, E Ma, HB Spinner, KLM Baney, J Chuck, ... Nature 566 (7743), 218-223, 2019 | 459 | 2019 |
| Disabling Cas9 by an anti-CRISPR DNA mimic J Shin, F Jiang, JJ Liu, NL Bray, BJ Rauch, SH Baik, E Nogales, ... Science advances 3 (7), e1701620, 2017 | 379 | 2017 |
| Structural basis for the modular recognition of single-stranded RNA by PPR proteins P Yin, Q Li, C Yan, Y Liu, J Liu, F Yu, Z Wang, J Long, J He, HW Wang, ... Nature 504 (7478), 168-171, 2013 | 361 | 2013 |
| A broad-spectrum inhibitor of CRISPR-Cas9 LB Harrington, KW Doxzen, E Ma, JJ Liu, GJ Knott, A Edraki, B Garcia, ... Cell 170 (6), 1224-1233. e15, 2017 | 297 | 2017 |
| Targeting apoptotic and autophagic pathways for cancer therapeutics J Liu, M Lin, J Yu, B Liu, J Bao Cancer letters 300 (2), 105-114, 2011 | 219 | 2011 |
| Cryo-EM structure of the exocyst complex K Mei, Y Li, S Wang, G Shao, J Wang, Y Ding, G Luo, P Yue, JJ Liu, ... Nature structural & molecular biology 25 (2), 139-146, 2018 | 156 | 2018 |
| Structures of the CRISPR genome integration complex AV Wright, JJ Liu, GJ Knott, KW Doxzen, E Nogales, JA Doudna Science 357 (6356), 1113-1118, 2017 | 154 | 2017 |
| Architecture of the ATG2B-WDR45 complex and an aromatic Y/HF motif crucial for complex formation JX Zheng, Y Li, YH Ding, JJ Liu, MJ Zhang, MQ Dong, HW Wang, L Yu Autophagy 13 (11), 1870-1883, 2017 | 138 | 2017 |
| Trifunctional cross-linker for mapping protein-protein interaction networks and comparing protein conformational states D Tan, Q Li, MJ Zhang, C Liu, C Ma, P Zhang, YH Ding, SB Fan, L Tao, ... Elife 5, e12509, 2016 | 132 | 2016 |
| Broad-spectrum enzymatic inhibition of CRISPR-Cas12a GJ Knott, BW Thornton, MJ Lobba, JJ Liu, B Al-Shayeb, KE Watters, ... Nature structural & molecular biology 26 (4), 315-321, 2019 | 124 | 2019 |
| Temperature-responsive competitive inhibition of CRISPR-Cas9 F Jiang, JJ Liu, BA Osuna, M Xu, JD Berry, BJ Rauch, E Nogales, ... Molecular cell 73 (3), 601-610. e5, 2019 | 79 | 2019 |
| SaCas9 requires 5′‐NNGRRT‐3′ PAM for sufficient cleavage and possesses higher cleavage activity than SpCas9 or FnCpf1 in human cells H Xie, L Tang, X He, X Liu, C Zhou, J Liu, X Ge, J Li, C Liu, J Zhao, J Qu, ... Biotechnology journal 13 (4), 1700561, 2018 | 79 | 2018 |
| Visualization of distinct substrate-recruitment pathways in the yeast exosome by EM JJ Liu, MA Bratkowski, X Liu, CY Niu, A Ke, HW Wang Nature structural & molecular biology 21 (1), 95-102, 2014 | 71 | 2014 |
| Polygonatum cyrtonema lectin induces murine fibrosarcoma L929 cell apoptosis and autophagy via blocking Ras–Raf and PI3K–Akt signaling pathways B Liu, J Wu, J Li, J Liu, W Li, C Li, H Xu, J Bao Biochimie 92 (12), 1934-1938, 2010 | 70 | 2010 |
| Cryo-EM structure and biochemical analysis reveal the basis of the functional difference between human PI3KC3-C1 and-C2 M Ma, JJ Liu, Y Li, Y Huang, N Ta, Y Chen, H Fu, MD Ye, Y Ding, ... Cell research 27 (8), 989-1001, 2017 | 60 | 2017 |
| A new type of ERGIC–ERES membrane contact mediated by TMED9 and SEC12 is required for autophagosome biogenesis S Li, R Yan, J Xu, S Zhao, X Ma, Q Sun, M Zhang, Y Li, JJG Liu, L Chen, ... Cell Research 32 (2), 119-138, 2022 | 59 | 2022 |
| Target preference of Type III-A CRISPR-Cas complexes at the transcription bubble TY Liu, JJ Liu, AJ Aditham, E Nogales, JA Doudna Nature communications 10 (1), 3001, 2019 | 56 | 2019 |
| Improved genome editing by an engineered CRISPR-Cas12a E Ma, K Chen, H Shi, EC Stahl, B Adler, M Trinidad, J Liu, K Zhou, J Ye, ... Nucleic Acids Research 50 (22), 12689-12701, 2022 | 54 | 2022 |
| Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity CA Tsuchida, S Zhang, MS Doost, Y Zhao, J Wang, E O’Brien, H Fang, ... Molecular cell 82 (6), 1199-1209. e6, 2022 | 54 | 2022 |
| Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a GJ Knott, BF Cress, JJ Liu, BW Thornton, RJ Lew, B Al-Shayeb, ... Elife 8, e49110, 2019 | 52 | 2019 |
Jennifer DoudnaProfessor of Molecular and Cell Biology and Chemistry, UC Berkeley在 berkeley.edu 的电子邮件经过验证