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| Looping and interaction between hypersensitive sites in the active β-globin locus B Tolhuis, RJ Palstra, E Splinter, F Grosveld, W De Laat Molecular cell 10 (6), 1453-1465, 2002 | 1740 | 2002 |
| Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture–on-chip (4C) M Simonis, P Klous, E Splinter, Y Moshkin, R Willemsen, E De Wit, ... Nature genetics 38 (11), 1348-1354, 2006 | 1684 | 2006 |
| Molecular mechanism of nucleotide excision repair WL de Laat, NGJ Jaspers, JHJ Hoeijmakers Genes & development 13 (7), 768-785, 1999 | 1487 | 1999 |
| A decade of 3C technologies: insights into nuclear organization E De Wit, W De Laat Genes & development 26 (1), 11-24, 2012 | 915 | 2012 |
| CTCF mediates long-range chromatin looping and local histone modification in the β-globin locus E Splinter, H Heath, J Kooren, RJ Palstra, P Klous, F Grosveld, N Galjart, ... Genes & development 20 (17), 2349-2354, 2006 | 909 | 2006 |
| Quantitative analysis of chromosome conformation capture assays (3C-qPCR) H Hagege, P Klous, C Braem, E Splinter, J Dekker, G Cathala, W De Laat, ... Nature protocols 2 (7), 1722-1733, 2007 | 781 | 2007 |
| A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia S Gröschel, MA Sanders, R Hoogenboezem, E de Wit, BAM Bouwman, ... Cell 157 (2), 369-381, 2014 | 752 | 2014 |
| CTCF binding polarity determines chromatin looping E de Wit, ESM Vos, SJB Holwerda, C Valdes-Quezada, MJAM Verstegen, ... Molecular cell 60 (4), 676-684, 2015 | 716 | 2015 |
| The β-globin nuclear compartment in development and erythroid differentiation RJ Palstra, B Tolhuis, E Splinter, R Nijmeijer, F Grosveld, W de Laat Nature genetics 35 (2), 190-194, 2003 | 707 | 2003 |
| Xeroderma pigmentosum group F caused by a defect in a structure-specific DNA repair endonuclease AM Sijbers, WL De Laat, RR Ariza, M Biggerstaff, YF Wei, JG Moggs, ... Cell 86 (5), 811-822, 1996 | 686 | 1996 |
| Topology of mammalian developmental enhancers and their regulatory landscapes W De Laat, D Duboule Nature 502 (7472), 499-506, 2013 | 618 | 2013 |
| eRNAs are required for p53-dependent enhancer activity and gene transcription CA Melo, J Drost, PJ Wijchers, H van de Werken, E de Wit, JAFO Vrielink, ... Molecular cell 49 (3), 524-535, 2013 | 587 | 2013 |
| A regulatory archipelago controls Hox genes transcription in digits T Montavon, N Soshnikova, B Mascrez, E Joye, L Thevenet, E Splinter, ... Cell 147 (5), 1132-1145, 2011 | 570 | 2011 |
| The dynamic architecture of Hox gene clusters D Noordermeer, M Leleu, E Splinter, J Rougemont, W De Laat, ... Science 334 (6053), 222-225, 2011 | 480 | 2011 |
| Spatial organization of gene expression: the active chromatin hub W de Laat, F Grosveld Chromosome Research 11, 447-459, 2003 | 479 | 2003 |
| The active spatial organization of the β-globin locus requires the transcription factor EKLF R Drissen, RJ Palstra, N Gillemans, E Splinter, F Grosveld, S Philipsen, ... Genes & development 18 (20), 2485-2490, 2004 | 476 | 2004 |
| DNA-binding polarity of human replication protein A positions nucleases in nucleotide excision repair WL De Laat, E Appeldoorn, K Sugasawa, E Weterings, NGJ Jaspers, ... Genes & development 12 (16), 2598-2609, 1998 | 474 | 1998 |
| Robust 4C-seq data analysis to screen for regulatory DNA interactions HJG Van De Werken, G Landan, SJB Holwerda, M Hoichman, P Klous, ... Nature methods 9 (10), 969-972, 2012 | 451 | 2012 |
| A genetic variant associated with five vascular diseases is a distal regulator of endothelin-1 gene expression RM Gupta, J Hadaya, A Trehan, SM Zekavat, C Roselli, D Klarin, ... Cell 170 (3), 522-533. e15, 2017 | 447 | 2017 |
Elzo de WitNetherlands Cancer Institute在 nki.nl 的电子邮件经过验证
