| Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints S Koyama, EA Akbay, YY Li, GS Herter-Sprie, KA Buczkowski, ... Nature communications 7 (1), 10501, 2016 | 1545 | 2016 |
| Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors EA Akbay, S Koyama, J Carretero, A Altabef, JH Tchaicha, ... Cancer discovery 3 (12), 1355-1363, 2013 | 1352 | 2013 |
| Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma PE Fecci, DA Mitchell, JF Whitesides, W Xie, AH Friedman, GE Archer, ... Cancer research 66 (6), 3294-3302, 2006 | 674 | 2006 |
| Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors P Chongsathidkiet, C Jackson, S Koyama, F Loebel, X Cui, SH Farber, ... Nature medicine 24 (9), 1459-1468, 2018 | 579 | 2018 |
| STK11/LKB1 deficiency promotes neutrophil recruitment and proinflammatory cytokine production to suppress T-cell activity in the lung tumor microenvironment S Koyama, EA Akbay, YY Li, AR Aref, F Skoulidis, GS Herter-Sprie, ... Cancer research 76 (5), 999-1008, 2016 | 576 | 2016 |
| Brain immunology and immunotherapy in brain tumours JH Sampson, MD Gunn, PE Fecci, DM Ashley Nature Reviews Cancer 20 (1), 12-25, 2020 | 574 | 2020 |
| T-cell exhaustion signatures vary with tumor type and are severe in glioblastoma K Woroniecka, P Chongsathidkiet, K Rhodin, H Kemeny, C Dechant, ... Clinical Cancer Research 24 (17), 4175-4186, 2018 | 559 | 2018 |
| Dexamethasone-induced immunosuppression: mechanisms and implications for immunotherapy AJ Giles, MKND Hutchinson, HM Sonnemann, J Jung, PE Fecci, ... Journal for immunotherapy of cancer 6, 1-13, 2018 | 441 | 2018 |
| Systemic CTLA-4 blockade ameliorates glioma-induced changes to the CD4+ T cell compartment without affecting regulatory T-cell function PE Fecci, H Ochiai, DA Mitchell, PM Grossi, AE Sweeney, GE Archer, ... Clinical cancer research 13 (7), 2158-2167, 2007 | 398 | 2007 |
| T-cell dysfunction in glioblastoma: applying a new framework KI Woroniecka, KE Rhodin, P Chongsathidkiet, KA Keith, PE Fecci Clinical Cancer Research 24 (16), 3792-3802, 2018 | 291 | 2018 |
| A review of glioblastoma immunotherapy R Medikonda, G Dunn, M Rahman, P Fecci, M Lim Journal of neuro-oncology 151, 41-53, 2021 | 249 | 2021 |
| Immune suppression in gliomas MM Grabowski, EW Sankey, KJ Ryan, P Chongsathidkiet, SJ Lorrey, ... Journal of neuro-oncology 151, 3-12, 2021 | 240 | 2021 |
| Multifaceted oncolytic virus therapy for glioblastoma in an immunocompetent cancer stem cell model TA Cheema, H Wakimoto, PE Fecci, J Ning, T Kuroda, DS Jeyaretna, ... Proceedings of the National Academy of Sciences 110 (29), 12006-12011, 2013 | 228 | 2013 |
| Systemic anti-CD25 monoclonal antibody administration safely enhances immunity in murine glioma without eliminating regulatory T cells PE Fecci, AE Sweeney, PM Grossi, SK Nair, CA Learn, DA Mitchell, X Cui, ... Clinical Cancer Research 12 (14), 4294-4305, 2006 | 213 | 2006 |
| Leptomeningeal disease: current diagnostic and therapeutic strategies. G Nayar, T Ejikeme, P Chongsathidkiet, AA Elsamadicy, KL Blackwell, ... Oncotarget 8 (42), 73312-73328, 2017 | 201 | 2017 |
| CD4 T-cell exhaustion: does it exist and what are its roles in cancer? AM Miggelbrink, JD Jackson, SJ Lorrey, ES Srinivasan, J Waibl-Polania, ... Clinical Cancer Research 27 (21), 5742-5752, 2021 | 179 | 2021 |
| Sequential immunotherapy by vaccination with GM-CSF–expressing glioma cells and CTLA-4 blockade effectively treats established murine intracranial tumors P Agarwalla, Z Barnard, P Fecci, G Dranoff, WT Curry Jr Journal of immunotherapy 35 (5), 385-389, 2012 | 130 | 2012 |
| The evolving modern management of brain metastasis PE Fecci, CD Champion, J Hoj, CM McKernan, CR Goodwin, ... Clinical Cancer Research 25 (22), 6570-6580, 2019 | 127 | 2019 |
| Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors Y Mei, WL Bi, NF Greenwald, Z Du, NYR Agar, UB Kaiser, ... Oncotarget 7 (47), 76565, 2016 | 124 | 2016 |
| Current multidisciplinary management of brain metastases MJ Moravan, PE Fecci, CK Anders, JM Clarke, AKS Salama, JD Adamson, ... Cancer 126 (7), 1390-1406, 2020 | 122 | 2020 |
John H. Sampson, M.D., Ph.D., M.H.Sc...Wilkins Distinguished Professor and Chief of Neurosurgery在 duke.edu 的电子邮件经过验证
