Immunological considerations for COVID-19 vaccine strategies M Jeyanathan, S Afkhami, F Smaill, MS Miller, BD Lichty, Z Xing Nature Reviews Immunology 20 (10), 615-632, 2020 | 1220 | 2020 |
Induction of autonomous memory alveolar macrophages requires T cell help and is critical to trained immunity Y Yao, M Jeyanathan, S Haddadi, NG Barra, M Vaseghi-Shanjani, ... Cell 175 (6), 1634-1650. e17, 2018 | 453 | 2018 |
Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2 S Afkhami, MR D’Agostino, A Zhang, HD Stacey, A Marzok, A Kang, ... Cell 185 (5), 896-915. e19, 2022 | 282 | 2022 |
Methods and clinical development of adenovirus-vectored vaccines against mucosal pathogens S Afkhami, Y Yao, Z Xing Molecular therapy Methods & clinical development 3, 2016 | 129 | 2016 |
COVID‐19: Current knowledge in clinical features, immunological responses, and vaccine development R Singh, A Kang, X Luo, M Jeyanathan, A Gillgrass, S Afkhami, Z Xing The FASEB Journal 35 (3), e21409, 2021 | 122 | 2021 |
Innate immune memory of tissue-resident macrophages and trained innate immunity: Re-vamping vaccine concept and strategies Z Xing, S Afkhami, J Bavananthasivam, DK Fritz, MR D’Agostino, ... Journal of Leucocyte Biology 108 (3), 825-834, 2020 | 88 | 2020 |
Aerosol delivery, but not intramuscular injection, of adenovirus-vectored tuberculosis vaccine induces respiratory-mucosal immunity in humans M Jeyanathan, DK Fritz, S Afkhami, E Aguirre, KJ Howie, A Zganiacz, ... JCI insight 7 (3), e155655, 2022 | 82 | 2022 |
New tuberculosis vaccine strategies: taking aim at un-natural immunity M Jeyanathan, Y Yao, S Afkhami, F Smaill, Z Xing Trends in immunology 39 (5), 419-433, 2018 | 78 | 2018 |
Parenteral BCG vaccine induces lung-resident memory macrophages and trained immunity via the gut–lung axis M Jeyanathan, M Vaseghi-Shanjani, S Afkhami, JA Grondin, A Kang, ... Nature immunology 23 (12), 1687-1702, 2022 | 76 | 2022 |
CXCR3 signaling is required for restricted homing of parenteral tuberculosis vaccine–induced T cells to both the lung parenchyma and airway M Jeyanathan, S Afkhami, A Khera, T Mandur, D Damjanovic, Y Yao, ... The Journal of Immunology 199 (7), 2555-2569, 2017 | 59 | 2017 |
Novel chimpanzee adenovirus-vectored respiratory mucosal tuberculosis vaccine: overcoming local anti-human adenovirus immunity for potent TB protection M Jeyanathan, N Thanthrige-Don, S Afkhami, R Lai, D Damjanovic, ... Mucosal immunology 8 (6), 1373-1387, 2015 | 59 | 2015 |
Experimental and natural evidence of SARS-CoV-2-infection-induced activation of type I interferon responses A Banerjee, N El-Sayes, P Budylowski, RA Jacob, D Richard, H Maan, ... IScience 24 (5), 2021 | 51 | 2021 |
Mucosal immunity and novel tuberculosis vaccine strategies: route of immunisation-determined T-cell homing to restricted lung mucosal compartments R Lai, S Afkhami, S Haddadi, M Jeyanathan, Z Xing European Respiratory Review 24 (136), 356-360, 2015 | 48 | 2015 |
Airway macrophages mediate mucosal vaccine–induced trained innate immunity against Mycobacterium tuberculosis in early stages of infection MR D’Agostino, R Lai, S Afkhami, A Khera, Y Yao, M Vaseghi-Shanjani, ... The Journal of Immunology 205 (10), 2750-2762, 2020 | 44 | 2020 |
Expression and role of VLA-1 in resident memory CD8 T cell responses to respiratory mucosal viral-vectored immunization against tuberculosis S Haddadi, N Thanthrige-Don, S Afkhami, A Khera, M Jeyanathan, Z Xing Scientific reports 7 (1), 9525, 2017 | 43 | 2017 |
Pulmonary M. tuberculosis infection delays Th1 immunity via immunoadaptor DAP12-regulated IRAK-M and IL-10 expression in antigen-presenting cells M Jeyanathan, S McCormick, R Lai, S Afkhami, CR Shaler, CN Horvath, ... Mucosal immunology 7 (3), 670-683, 2014 | 43 | 2014 |
Mucosal-pull induction of lung-resident memory CD8 T cells in parenteral TB vaccine-primed hosts requires cognate antigens and CD4 T cells S Haddadi, M Vaseghi-Shanjani, Y Yao, S Afkhami, MR D'Agostino, ... Frontiers in immunology 10, 2075, 2019 | 42 | 2019 |
CD11b+ dendritic cell–mediated anti–Mycobacterium tuberculosis Th1 activation is counterregulated by CD103+ dendritic cells via IL-10 R Lai, M Jeyanathan, S Afkhami, A Zganiacz, JA Hammill, Y Yao, ... The Journal of Immunology 200 (5), 1746-1760, 2018 | 42 | 2018 |
Spray dried human and chimpanzee adenoviral-vectored vaccines are thermally stable and immunogenic in vivo S Afkhami, DA LeClair, S Haddadi, R Lai, SP Toniolo, HC Ertl, ... Vaccine 35 (22), 2916-2924, 2017 | 41 | 2017 |
Excipient selection for thermally stable enveloped and non-enveloped viral vaccine platforms in dry powders SP Toniolo, S Afkhami, A Mahmood, C Fradin, BD Lichty, MS Miller, ... International Journal of Pharmaceutics 561, 66-73, 2019 | 37 | 2019 |