| HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption I Papandreou, RA Cairns, L Fontana, AL Lim, NC Denko Cell metabolism 3 (3), 187-197, 2006 | 2688 | 2006 |
| Hypoxia, HIF1 and glucose metabolism in the solid tumour NC Denko Nature Reviews Cancer 8 (9), 705-713, 2008 | 2002 | 2008 |
| XBP1 is essential for survival under hypoxic conditions and is required for tumor growth L Romero-Ramirez, H Cao, D Nelson, E Hammond, AH Lee, H Yoshida, ... Cancer research 64 (17), 5943-5947, 2004 | 702 | 2004 |
| FoxO3 regulates neural stem cell homeostasis VM Renault, VA Rafalski, AA Morgan, DAM Salih, JO Brett, AE Webb, ... Cell stem cell 5 (5), 527-539, 2009 | 654 | 2009 |
| Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma I Papandreou, NC Denko, M Olson, H Van Melckebeke, S Lust, A Tam, ... Blood, The Journal of the American Society of Hematology 117 (4), 1311-1314, 2011 | 551 | 2011 |
| Candidate genes for the hypoxic tumor phenotype AC Koong, NC Denko, KM Hudson, C Schindler, L Swiersz, C Koch, ... Cancer research 60 (4), 883-887, 2000 | 451 | 2000 |
| Overcoming physiologic barriers to cancer treatment by molecularly targeting the tumor microenvironment R Cairns, I Papandreou, N Denko Molecular Cancer Research 4 (2), 61-70, 2006 | 438 | 2006 |
| Hypoxia links ATR and p53 through replication arrest EM Hammond, NC Denko, MJ Dorie, RT Abraham, AJ Giaccia Molecular and cellular biology 22 (6), 1834-1843, 2002 | 412 | 2002 |
| Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3, and BNIP3L I Papandreou, AL Lim, K Laderoute, NC Denko Cell Death & Differentiation 15 (10), 1572-1581, 2008 | 411 | 2008 |
| Investigating hypoxic tumor physiology through gene expression patterns NC Denko, LA Fontana, KM Hudson, PD Sutphin, S Raychaudhuri, ... Oncogene 22 (37), 5907-5914, 2003 | 411 | 2003 |
| Hypoxic regulation of glutamine metabolism through HIF1 and SIAH2 supports lipid synthesis that is necessary for tumor growth RC Sun, NC Denko Cell metabolism 19 (2), 285-292, 2014 | 381 | 2014 |
| Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1α DA Chan, PD Sutphin, NC Denko, AJ Giaccia Journal of biological chemistry 277 (42), 40112-40117, 2002 | 352 | 2002 |
| Hypoxia induces a novel signature of chromatin modifications and global repression of transcription AB Johnson, N Denko, MC Barton Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 640 (1 …, 2008 | 313 | 2008 |
| Hypoxic gene expression and metastasis QT Le, NC Denko, AJ Giaccia Cancer and Metastasis Reviews 23, 293-310, 2004 | 292 | 2004 |
| The human Ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle. NC Denko, AJ Giaccia, JR Stringer, PJ Stambrook Proceedings of the National Academy of Sciences 91 (11), 5124-5128, 1994 | 280 | 1994 |
| Oxygen consumption can regulate the growth of tumors, a new perspective on the Warburg effect Y Chen, R Cairns, I Papandreou, A Koong, NC Denko PloS one 4 (9), e7033, 2009 | 236 | 2009 |
| Metabolic targeting of hypoxia and HIF1 in solid tumors can enhance cytotoxic chemotherapy RA Cairns, I Papandreou, PD Sutphin, NC Denko Proceedings of the National Academy of Sciences 104 (22), 9445-9450, 2007 | 218 | 2007 |
| Epigenetic regulation of gene expression in cervical cancer cells by the tumor microenvironment N Denko, C Schindler, A Koong, K Laderoute, C Green, A Giaccia Clinical Cancer Research 6 (2), 480-487, 2000 | 210 | 2000 |
| Hypoxic Activation of Nuclear Factor-κB Is Mediated by a Ras and Raf Signaling Pathway and Does Not Involve MAP Kinase (ERK1 or ERK2) AC Koong, EY Chen, NF Mivechi, NC Denko, P Stambrook, AJ Giaccia Cancer research 54 (20), 5273-5279, 1994 | 208 | 1994 |
| Anticancer drugs that target metabolism: Is dichloroacetate the new paradigm? I Papandreou, T Goliasova, NC Denko International journal of cancer 128 (5), 1001-1008, 2011 | 204 | 2011 |
Quynh-Thu LeProfessor, stanford university在 stanford.edu 的電子郵件地址已通過驗證