Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer BB de Jesus, E Vera, K Schneeberger, AM Tejera, E Ayuso, F Bosch, ... EMBO molecular medicine 4 (8), 691-704, 2012 | 666 | 2012 |
Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells RM Marion, K Strati, H Li, A Tejera, S Schoeftner, S Ortega, M Serrano, ... Cell stem cell 4 (2), 141-154, 2009 | 616 | 2009 |
Telomerase reverse transcriptase delays aging in cancer-resistant mice A Tomas-Loba, I Flores, PJ Fernandez-Marcos, ML Cayuela, A Maraver, ... Cell 135 (4), 609-622, 2008 | 607 | 2008 |
Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice P Martínez, M Thanasoula, P Muñoz, C Liao, A Tejera, C McNees, ... Genes & development 23 (17), 2060-2075, 2009 | 439 | 2009 |
The longest telomeres: a general signature of adult stem cell compartments I Flores, A Canela, E Vera, A Tejera, G Cotsarelis, MA Blasco Genes & development 22 (5), 654-667, 2008 | 427 | 2008 |
The telomerase activator TA‐65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence BB de Jesus, K Schneeberger, E Vera, A Tejera, CB Harley, MA Blasco Aging cell 10 (4), 604-621, 2011 | 393 | 2011 |
Mammalian Rap1 controls telomere function and gene expression through binding to telomeric and extratelomeric sites P Martinez, M Thanasoula, AR Carlos, G Gómez-López, AM Tejera, ... Nature cell biology 12 (8), 768-780, 2010 | 331 | 2010 |
A G-quadruplex ligand with 10000-fold selectivity over duplex DNA IM Dixon, F Lopez, AM Tejera, JP Estève, MA Blasco, G Pratviel, ... Journal of the American Chemical Society 129 (6), 1502-1503, 2007 | 285 | 2007 |
The copper‐chelating agent, trientine, suppresses tumor development and angiogenesis in the murine hepatocellular carcinoma cells J Yoshii, H Yoshiji, S Kuriyama, Y Ikenaka, R Noguchi, H Okuda, ... International journal of cancer 94 (6), 768-773, 2001 | 195 | 2001 |
Porphyrin derivatives for telomere binding and telomerase inhibition IM Dixon, F Lopez, JP Estève, AM Tejera, MA Blasco, G Pratviel, ... ChemBioChem 6 (1), 123-132, 2005 | 184 | 2005 |
Telomerase expression confers cardioprotection in the adult mouse heart after acute myocardial infarction C Bär, BB De Jesus, R Serrano, A Tejera, E Ayuso, V Jimenez, ... Nature communications 5, 5863, 2014 | 171 | 2014 |
TPP1 is required for TERT recruitment, telomere elongation during nuclear reprogramming, and normal skin development in mice AM Tejera, MS d'Alcontres, M Thanasoula, RM Marion, P Martinez, C Liao, ... Developmental cell 18 (5), 775-789, 2010 | 162 | 2010 |
Irreversible telomere shortening by 3′-azido-2′, 3′-dideoxythymidine (AZT) treatment DE Gomez, AM Tejera, OA Olivero Biochemical and biophysical research communications 246 (1), 107-110, 1998 | 139 | 1998 |
Therapeutic effects of telomerase in mice with pulmonary fibrosis induced by damage to the lungs and short telomeres JM Povedano, P Martinez, R Serrano, Á Tejera, G Gómez-López, ... Elife 7, e31299, 2018 | 135 | 2018 |
Localization-dependent and-independent roles of SLX4 in regulating telomeres JSJ Wilson, AM Tejera, D Castor, R Toth, MA Blasco, J Rouse Cell reports 4 (5), 853-860, 2013 | 103 | 2013 |
Expression of mTert in primary murine cells links the growth-promoting effects of telomerase to transforming growth factor-β signaling C Geserick, A Tejera, E Gonzalez-Suarez, P Klatt, MA Blasco Oncogene 25 (31), 4310-4319, 2006 | 88 | 2006 |
ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase CJ McNees, AM Tejera, P Martínez, M Murga, F Mulero, ... The Journal of cell biology 188 (5), 639-652, 2010 | 86 | 2010 |
Zidovudine induces S-phase arrest and cell cycle gene expression changes in human cells OA Olivero, AM Tejera, JJ Fernandez, BJ Taylor, S Das, RL Divi, ... Mutagenesis 20 (2), 139-146, 2005 | 81 | 2005 |
Generation of mice with longer and better preserved telomeres in the absence of genetic manipulations E Varela, MA Muñoz-Lorente, AM Tejera, S Ortega, MA Blasco Nature communications 7, 11739, 2016 | 69 | 2016 |
Inhibition of mammary tumor cell adhesion, migration, and invasion by the selective synthetic urokinase inhibitor B428. DF Alonso, AM Tejera, EF Farias, EKJ Bal, DE Gomez Anticancer research 18 (6A), 4499-4504, 1998 | 69 | 1998 |