Vascularization strategies in bone tissue engineering

F Simunovic, G Finkenzeller - Cells, 2021 - mdpi.com
Bone is a highly vascularized tissue, and its development, maturation, remodeling, and
regeneration are dependent on a tight regulation of blood vessel supply. This condition also …

Prevascularization in tissue engineering: current concepts and future directions

MW Laschke, MD Menger - Biotechnology advances, 2016 - Elsevier
The survival of engineered tissue constructs during the initial phase after their implantation
depends on the rapid development of an adequate vascularization. This, in turn, is a major …

Osteochondral tissue engineering: scaffolds, stem cells and applications

P Nooeaid, V Salih, JP Beier… - Journal of cellular and …, 2012 - Wiley Online Library
Osteochondral tissue engineering has shown an increasing development to provide suitable
strategies for the regeneration of damaged cartilage and underlying subchondral bone …

Cell-free and cell-based approaches for bone regeneration

EM Bueno, J Glowacki - Nature Reviews Rheumatology, 2009 - nature.com
The clinical augmentation of bone currently involves the use of autogenous or allogeneic
bone grafts and synthetic materials, all of which are associated with limitations. Research on …

A short discourse on vascular tissue engineering

WG Chang, LE Niklason - NPJ Regenerative medicine, 2017 - nature.com
Vascular tissue engineering has significant potential to make a major impact on a wide array
of clinical problems. Continued progress in understanding basic vascular biology will be …

Hypoxia in static and dynamic 3D culture systems for tissue engineering of bone

E Volkmer, I Drosse, S Otto, A Stangelmayer… - … Engineering Part A, 2008 - liebertpub.com
Tissue engineering of sizeable cell-scaffold constructs is limited by gradients in tissue
quality from the periphery toward the center. Because homogenous delivery of oxygen to …

Tissue engineering for bone defect healing: an update on a multi-component approach

I Drosse, E Volkmer, R Capanna, P De Biase… - Injury, 2008 - Elsevier
The need for an interdisciplinary approach in order to establish new therapeutic strategies
for the therapy of bone defects has been acknowledged by the scientific community for many …

Fabrication techniques for vascular and vascularized tissue engineering

Z Wang, SM Mithieux, AS Weiss - Advanced healthcare …, 2019 - Wiley Online Library
Impaired or damaged blood vessels can occur at all levels in the hierarchy of vascular
systems from large vasculatures such as arteries and veins to meso‐and microvasculatures …

Tissue engineered bone grafts: biological requirements, tissue culture and clinical relevance

M Frohlich, WL Grayson, LQ Wan… - Current stem cell …, 2008 - ingentaconnect.com
The tremendous need for bone tissue in numerous clinical situations and the limited
availability of suitable bone grafts are driving the development of tissue engineering …

[HTML][HTML] Tissue engineered bone grafts: biological requirements, tissue culture and clinical relevance

M Fröhlich, WL Grayson, LQ Wan, D Marolt… - Current stem cell …, 2008 - ncbi.nlm.nih.gov
The tremendous need for bone tissue in numerous clinical situations and the limited
availability of suitable bone grafts are driving the development of tissue engineering …