Diabetic kidney diseases revisited: A new perspective for a new era
Background Globally, diabetic kidney disease (DKD) is the leading cause of end-stage renal
disease. As the most common microvascular complication of diabetes, DKD is a thorny …
disease. As the most common microvascular complication of diabetes, DKD is a thorny …
Recent advances in diabetic kidney diseases: from kidney injury to kidney fibrosis
PH Hung, YC Hsu, TH Chen, CL Lin - International Journal of Molecular …, 2021 - mdpi.com
Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease and end-
stage renal disease. The natural history of DKD includes glomerular hyperfiltration …
stage renal disease. The natural history of DKD includes glomerular hyperfiltration …
Environmental chemical exposures and human epigenetics
L Hou, X Zhang, D Wang… - International journal of …, 2012 - academic.oup.com
Every year more than 13 million deaths worldwide are due to environmental pollutants, and
approximately 24% of diseases are caused by environmental exposures that might be …
approximately 24% of diseases are caused by environmental exposures that might be …
The role of epigenetics in the pathology of diabetic complications
LM Villeneuve, R Natarajan - American Journal of …, 2010 - journals.physiology.org
Diabetes is associated with significantly accelerated rates of several debilitating
microvascular complications such as nephropathy, retinopathy, and neuropathy, and …
microvascular complications such as nephropathy, retinopathy, and neuropathy, and …
Effects of metabolic memory on inflammation and fibrosis associated with diabetic kidney disease: an epigenetic perspective
W Zheng, J Guo, ZS Liu - Clinical epigenetics, 2021 - Springer
Diabetic kidney disease (DKD) is one of the most common microvascular complication of
both type 1 (T1DM) and type 2 diabetes mellitus (T2DM), and the leading cause of end …
both type 1 (T1DM) and type 2 diabetes mellitus (T2DM), and the leading cause of end …
New insights into molecular mechanisms of diabetic kidney disease
Diabetic kidney disease remains a major microvascular complication of diabetes and the
most common cause of chronic kidney failure requiring dialysis in the United States. Medical …
most common cause of chronic kidney failure requiring dialysis in the United States. Medical …
Gut microbial metabolite butyrate protects against proteinuric kidney disease through epigenetic‐and GPR109a‐mediated mechanisms
Butyrate is a short‐chain fatty acid derived from the metabolism of indigestible
carbohydrates by the gut microbiota. Butyrate contributes to gut homeostasis, but it may also …
carbohydrates by the gut microbiota. Butyrate contributes to gut homeostasis, but it may also …
Systematic integrated analysis of genetic and epigenetic variation in diabetic kidney disease
Poor metabolic control and host genetic predisposition are critical for diabetic kidney
disease (DKD) development. The epigenome integrates information from sequence …
disease (DKD) development. The epigenome integrates information from sequence …
Targeting epigenetic DNA and histone modifications to treat kidney disease
M Fontecha-Barriuso, D Martin-Sanchez… - Nephrology dialysis …, 2018 - academic.oup.com
Epigenetics refers to heritable changes in gene expression patterns not caused by an
altered nucleotide sequence, and includes non-coding RNAs and covalent modifications of …
altered nucleotide sequence, and includes non-coding RNAs and covalent modifications of …
Genetic and epigenetic studies in diabetic kidney disease
HF Gu - Frontiers in genetics, 2019 - frontiersin.org
Chronic kidney disease is a worldwide health crisis, while diabetic kidney disease (DKD)
has become the leading cause of end-stage renal disease (ESRD). DKD is a microvascular …
has become the leading cause of end-stage renal disease (ESRD). DKD is a microvascular …