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Recent progress concerning CpG DNA and its use as a vaccine adjuvant
H Shirota, DM Klinman - Expert review of vaccines, 2014 - Taylor & Francis
CpG Oligonucleotides (ODN) are immunomodulatory synthetic oligonucleotides designed to
specifically agonize Toll-like receptor 9. Here, we review recent progress in understanding …
specifically agonize Toll-like receptor 9. Here, we review recent progress in understanding …
Transcutaneous immunization: an overview of advantages, disease targets, vaccines, and delivery technologies
Skin is an immunologically active tissue composed of specialized cells and agents that
capture and process antigens to confer immune protection. Transcutaneous immunization …
capture and process antigens to confer immune protection. Transcutaneous immunization …
The oral administration of bacterial extracts prevents asthma via the recruitment of regulatory T cells to the airways
S Navarro, G Cossalter, C Chiavaroli, A Kanda… - Mucosal …, 2011 - nature.com
The prevalence of asthma has steadily increased during the last decade, probably as the
result of changes in the environment, including reduced microbial exposure during infancy …
result of changes in the environment, including reduced microbial exposure during infancy …
Intranasal Vaccination with a Secreted Chlamydial Protein Enhances Resolution of Genital Chlamydia muridarum Infection, Protects against Oviduct Pathology, and …
There is currently no licensed vaccine against Chlamydia trachomatis, the leading cause of
sexually transmitted bacterial disease worldwide. Conventional vaccination attempts using …
sexually transmitted bacterial disease worldwide. Conventional vaccination attempts using …
Interleukin-13 promotes susceptibility to chlamydial infection of the respiratory and genital tracts
Chlamydiae are intracellular bacteria that commonly cause infections of the respiratory and
genital tracts, which are major clinical problems. Infections are also linked to the aetiology of …
genital tracts, which are major clinical problems. Infections are also linked to the aetiology of …
The Duration of Chlamydia muridarum Genital Tract Infection and Associated Chronic Pathological Changes Are Reduced in IL-17 Knockout Mice but Protection Is …
DW Andrew, M Cochrane, JH Schripsema… - PloS one, 2013 - journals.plos.org
IL-17 is believed to be important for protection against extracellular pathogens, where
clearance is dependent on neutrophil recruitment and local activation of epithelial cell …
clearance is dependent on neutrophil recruitment and local activation of epithelial cell …
TLR2, but Not TLR4, Is Required for Effective Host Defence against Chlamydia Respiratory Tract Infection in Early Life
Chlamydia pneumoniae commonly causes respiratory tract infections in children, and
epidemiological investigations strongly link infection to the pathogenesis of asthma. The …
epidemiological investigations strongly link infection to the pathogenesis of asthma. The …
Assessment of evidence for or against contributions of Chlamydia pneumoniae infections to Alzheimer's disease etiology
JJ Woods, KA Skelding, KL Martin, R Aryal… - Brain, behavior, and …, 2020 - Elsevier
Alzheimer's disease, the most common form of dementia, was first formally described in
1907 yet its etiology has remained elusive. Recent proposals that Aβ peptide may be part of …
1907 yet its etiology has remained elusive. Recent proposals that Aβ peptide may be part of …
A Multi‐Subunit Chlamydial Vaccine Induces Antibody and Cell‐Mediated Immunity in Immunized Koalas (Phascolarctos cinereus): Comparison of Three Different …
Citation Carey AJ, Timms P, Rawlinson G, Brumm J, Nilsson K, Harris JM, Beagley KW. A
multi‐subunit chlamydial vaccine induces antibody and cell‐mediated immunity in …
multi‐subunit chlamydial vaccine induces antibody and cell‐mediated immunity in …
Intranasal immunization with chlamydial protease-like activity factor and CpG deoxynucleotides enhances protective immunity against genital Chlamydia muridarum …
We have reported recently that intranasal (in) vaccination with chlamydial protease-like
activity factor (CPAF) and interleukin-12 (IL-12) enhances protective immunity against …
activity factor (CPAF) and interleukin-12 (IL-12) enhances protective immunity against …