Colloidal nanoparticles as advanced biological sensors
Background Nanoparticle biosensors have the potential to enhance or supersede current
analytical techniques, and their introduction could have a great impact in research and …
analytical techniques, and their introduction could have a great impact in research and …
Nexus between in silico and in vivo models to enhance clinical translation of nanomedicine
In cancer, one of the main barriers to effective chemotherapy is inefficient drug delivery. The
delivery of drugs to solid tumors involves various biochemical, biophysical, and mechanical …
delivery of drugs to solid tumors involves various biochemical, biophysical, and mechanical …
Recent developments in chemical conjugation strategies targeting native amino acids in proteins and their applications in antibody–drug conjugates
MS Kang, TWS Kong, JYX Khoo, TP Loh - Chemical Science, 2021 - pubs.rsc.org
Many fields in chemical biology and synthetic biology require effective bioconjugation
methods to achieve their desired functions and activities. Among such biomolecule …
methods to achieve their desired functions and activities. Among such biomolecule …
Effects of surface compositional and structural heterogeneity on nanoparticle–protein interactions: different protein configurations
As nanoparticles (NPs) enter into biological systems, they are immediately exposed to a
variety and concentration of proteins. The physicochemical interactions between proteins …
variety and concentration of proteins. The physicochemical interactions between proteins …
Mathematical and computational modeling of nano-engineered drug delivery systems
While the advent of nano-engineered drug delivery systems (DDSs) has revived hopes for
better management of a wide range of pathologies, critical appraisal of the field has shown …
better management of a wide range of pathologies, critical appraisal of the field has shown …
Gold nanoparticles with patterned surface monolayers for nanomedicine: current perspectives
Molecular self-assembly is a topic attracting intense scientific interest. Various strategies
have been developed for construction of molecular aggregates with rationally designed …
have been developed for construction of molecular aggregates with rationally designed …
Fine-tuning the antimicrobial profile of biocompatible gold nanoparticles by sequential surface functionalization using polyoxometalates and lysine
Antimicrobial action of nanomaterials is typically assigned to the nanomaterial composition,
size and/or shape, whereas influence of complex corona stabilizing the nanoparticle surface …
size and/or shape, whereas influence of complex corona stabilizing the nanoparticle surface …
Protein–nanoparticle interactions: the effects of surface compositional and structural heterogeneity are scale dependent
Nanoparticles (NPs) in the biological environment are exposed to a large variety and
concentration of proteins. Proteins are known to adsorb in a 'corona'like structure on the …
concentration of proteins. Proteins are known to adsorb in a 'corona'like structure on the …
Binding parameters and molecular dynamics of β-lactoglobulin-vanillic acid complexation as a function of pH–Part A: Acidic pH
Protein-phenolic compound interactions are commonly investigated with inappropriate
linear equations for the analysis of binding strength and stoichiometry. This work utilises …
linear equations for the analysis of binding strength and stoichiometry. This work utilises …
The role of natural processes and surface energy of inhaled engineered nanoparticles on aggregation and corona formation
A Tsuda, NV Konduru - NanoImpact, 2016 - Elsevier
The surface chemistry of engineered nanoparticles (ENPs) becomes more important as their
size decreases and enters the nanometer-range. This review explains the fundamental …
size decreases and enters the nanometer-range. This review explains the fundamental …