[HTML][HTML] Toward a global virus genomic surveillance network
The COVID-19 pandemic galvanized the field of virus genomic surveillance, demonstrating
its utility for public health. Now, we must harness the momentum that led to increased …
its utility for public health. Now, we must harness the momentum that led to increased …
Establishment and lineage dynamics of the SARS-CoV-2 epidemic in the UK
The United Kingdom's COVID-19 epidemic during early 2020 was one of world's largest and
was unusually well represented by virus genomic sampling. We determined the fine-scale …
was unusually well represented by virus genomic sampling. We determined the fine-scale …
Generation of SARS-CoV-2 escape mutations by monoclonal antibody therapy
COVID-19 patients at risk of severe disease may be treated with neutralising monoclonal
antibodies (mAbs). To minimise virus escape from neutralisation these are administered as …
antibodies (mAbs). To minimise virus escape from neutralisation these are administered as …
Global disparities in SARS-CoV-2 genomic surveillance
Genomic sequencing is essential to track the evolution and spread of SARS-CoV-2, optimize
molecular tests, treatments, vaccines, and guide public health responses. To investigate the …
molecular tests, treatments, vaccines, and guide public health responses. To investigate the …
Comparative transmission of SARS-CoV-2 Omicron (B. 1.1. 529) and Delta (B. 1.617. 2) variants and the impact of vaccination: national cohort study, England
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant (B.
1.1. 529) rapidly replaced Delta (B. 1.617. 2) to become dominant in England. Our study …
1.1. 529) rapidly replaced Delta (B. 1.617. 2) to become dominant in England. Our study …
Recurrent SARS-CoV-2 mutations in immunodeficient patients
Long-term severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in
immunodeficient patients are an important source of variation for the virus but are …
immunodeficient patients are an important source of variation for the virus but are …
A daily-updated database and tools for comprehensive SARS-CoV-2 mutation-annotated trees
The vast scale of SARS-CoV-2 sequencing data has made it increasingly challenging to
comprehensively analyze all available data using existing tools and file formats. To address …
comprehensively analyze all available data using existing tools and file formats. To address …
Generation of synthetic chest X-ray images and detection of COVID-19: A deep learning based approach
COVID-19 is a disease caused by the SARS-CoV-2 virus. The COVID-19 virus spreads
when a person comes into contact with an affected individual. This is mainly through drops …
when a person comes into contact with an affected individual. This is mainly through drops …
[HTML][HTML] City-wide wastewater genomic surveillance through the successive emergence of SARS-CoV-2 Alpha and Delta variants
Genomic surveillance of SARS-CoV-2 has provided a critical evidence base for public
health decisions throughout the pandemic. Sequencing data from clinical cases has helped …
health decisions throughout the pandemic. Sequencing data from clinical cases has helped …
[HTML][HTML] Directions of change in intrinsic case severity across successive SARS-CoV-2 variant waves have been inconsistent
Objectives To determine how the intrinsic severity of successively dominant SARS-CoV-2
variants changed over the course of the pandemic. Methods A retrospective cohort analysis …
variants changed over the course of the pandemic. Methods A retrospective cohort analysis …