Clinical research is an alternative terminology used to describe medical research. Clinical
research involves people, and it is generally carried out to evaluate the efficacy of a …

Literature and experimental data relevant to waiver of in vivo bioequivalence (BE) testing for
the approval of immediate-release solid oral dosage forms containing amoxicillin trihydrate …

During antibiotic treatments, active residuals reaching the colon profoundly affect the
bacterial flora resulting in the emergence of resistance. To prevent these effects, we …

Rifaximin is an antibiotic, locally acting in the gastrointestinal tract, which may exist in
different crystal as well as amorphous forms. The branded rifaximin formulation contains the …

A multi-national working group on antibiotic stewardship, from the International Society of
Chemotherapy, put together ten recommendations to physicians prescribing antibiotics to …

The main goal of early phase trials is to gain knowledge about the clinical suitability of novel
compounds, without pursuing specific therapeutic purposes. Healthy volunteers usually …

Background The economic crisis in Sri Lanka has disarrayed the country's healthcare
services, posing a challenge to people with chronic diseases on routine care. This study …

Background. Concerns have recently emerged about the efficacy and the quality of
antibacterial generic products approved for use in humans. Methods. We searched Medline …

There are recently published arguments suggesting all generic antibiotic drugs do not
present the full reliability needed to claim therapeutic equivalence with branded drugs. The …

Study Objective Generic drugs contain identical active ingredients as their corresponding
brand drugs and are pharmaceutically equivalent and bioequivalent, whereas authorized …