Mounting evidence has shown that gut microbiome is associated with various cancers,
including gastrointestinal (GI) tract and non-GI tract cancers. But microbiome data have …

Due to the development of next-generation sequencing technology and an increased
appreciation of their role in modulating host immunity and their potential as therapeutic …

Though statistical normalizations are often used in differential abundance or differential
expression analysis to address sample-to-sample variation in sequencing depth, we offer a …

Introduction Disparities in incidence and outcome of rectal cancer are multifactorial in
etiology but may be due, in part, to differences in gut microbiome composition. We used …

In high-throughput sequencing (HTS) studies, sample-to-sample variation in sequencing
depth is driven by technical factors, and not by variation in the scale (eg, total size, microbial …