Statistical normalization methods in microbiome data with application to microbiome cancer research
Y **a - Gut Microbes, 2023 - Taylor & Francis
Mounting evidence has shown that gut microbiome is associated with various cancers,
including gastrointestinal (GI) tract and non-GI tract cancers. But microbiome data have …
including gastrointestinal (GI) tract and non-GI tract cancers. But microbiome data have …
[HTML][HTML] Review and revamp of compositional data transformation: A new framework combining proportion conversion and contrast transformation
Due to the development of next-generation sequencing technology and an increased
appreciation of their role in modulating host immunity and their potential as therapeutic …
appreciation of their role in modulating host immunity and their potential as therapeutic …
[HTML][HTML] Beyond Normalization: Incorporating Scale Uncertainty in Microbiome and Gene Expression Analysis
Though statistical normalizations are often used in differential abundance or differential
expression analysis to address sample-to-sample variation in sequencing depth, we offer a …
expression analysis to address sample-to-sample variation in sequencing depth, we offer a …
Assessment of Distinct Gut Microbiome Signatures in a Diverse Cohort of Patients Undergoing Definitive Treatment for Rectal Cancer
DM Hein, LA Coughlin, N Poulides… - Journal of …, 2024 - meridian.allenpress.com
Introduction Disparities in incidence and outcome of rectal cancer are multifactorial in
etiology but may be due, in part, to differences in gut microbiome composition. We used …
etiology but may be due, in part, to differences in gut microbiome composition. We used …