Emerging methylation-based approaches in microbiome engineering

C Won, SS Yim - Biotechnology for Biofuels and Bioproducts, 2024 - Springer
Bacterial epigenetics, particularly through DNA methylation, exerts significant influence over
various biological processes such as DNA replication, uptake, and gene regulation in …

Restriction endonuclease-based modification-dependent enrichment (REMoDE) of DNA for metagenomic sequencing

SU Enam, JL Cherry, SR Leonard… - Applied and …, 2023 - Am Soc Microbiol
Metagenomic sequencing is a swift and powerful tool to ascertain the presence of an
organism of interest in a sample. However, sequencing coverage of the organism of interest …

Critical assessment of nanopore sequencing for the detection of multiple forms of DNA modifications

Y Kong, Y Zhang, EA Mead, H Chen, CE Loo, Y Fan… - bioRxiv, 2024 - biorxiv.org
While nanopore sequencing is increasingly used for map** DNA modifications, it is
important to recognize false positive calls as they can mislead biological interpretations. To …

LongTrack: long read metagenomics-based precise tracking of bacterial strains and their genomic changes after fecal microbiota transplantation

Y Fan, M Ni, V Aggarwala, EA Mead, M Ksiezarek… - bioRxiv, 2024 - biorxiv.org
Fecal microbiota transplantation (FMT) has revolutionized the treatment of recurrent
Clostridioides difficile infection (rCDI) and is being evaluated across other diseases …

HIGH-THROUGHPUT DISENTANGLEMENT OF ENVIRONMENTAL MICROBIOMES: The Writing of Microflora Danica–The Microbiome of Denmark

TBN Jensen - 2024 - vbn.aau.dk
Aalborg Universitet HIGH-THROUGHPUT DISENTANGLEMENT OF ENVIRONMENTAL
MICROBIOMES The Writing of Microflora Danica – The Microb Page 1 Aalborg Universitet …

Unraveling host regulation of gut microbiota through the epigenome–microbiome axis

ML Pepke, SB Hansen, MT Limborg - Trends in Microbiology, 2024 - cell.com
Recent studies of dynamic interactions between epigenetic modifications of a host organism
and the composition or activity of its associated gut microbiota suggest an opportunity for the …