Quantitative clinical nuclear cardiology, part 2: Evolving/emerging applications

PJ Slomka, JB Moody, RJH Miller, JM Renaud… - Journal of Nuclear …, 2021 - Elsevier
Quantitative analysis has been applied extensively to image processing and interpretation in
nuclear cardiology to improve disease diagnosis and risk stratification. This is Part 2 of a two …

Automatic inter-frame patient motion correction for dynamic cardiac PET using deep learning

L Shi, Y Lu, N Dvornek, CA Weyman… - IEEE transactions on …, 2021 - ieeexplore.ieee.org
Patient motion during dynamic PET imaging can induce errors in myocardial blood flow
(MBF) estimation. Motion correction for dynamic cardiac PET is challenging because the …

Integrated myocardial flow reserve (iMFR) assessment: diffuse atherosclerosis and microvascular dysfunction are more strongly associated with mortality than focally …

JB Moody, A Poitrasson-Rivière, JM Renaud… - European Journal of …, 2023 - Springer
Background and aims Although treatment of ischemia-causing epicardial stenoses may
improve symptoms of ischemia, current evidence does not suggest that revascularization …

Multicenter evaluation of the feasibility of clinical implementation of SPECT myocardial blood flow measurement: intersite variability and imaging time

RG Wells, FM Bengel, L Camoni… - Circulation …, 2023 - Am Heart Assoc
Background: Single-center studies have shown that single photon emission computed
tomography myocardial blood flow (MBF) measurement is accurate compared with MBF …

Data-driven voluntary body motion detection and non-rigid event-by-event correction for static and dynamic PET

Y Lu, JD Gallezot, M Naganawa, S Ren… - Physics in Medicine …, 2019 - iopscience.iop.org
PET has the potential to perform absolute in vivo radiotracer quantitation. This potential can
be compromised by voluntary body motion (BM), which degrades image resolution, alters …

Myocardial flow reserve estimation with contemporary CZT-SPECT and 99mTc-tracers lacks precision for routine clinical application

JM Renaud, A Poitrasson-Riviere, T Hagio… - Journal of Nuclear …, 2022 - Elsevier
Background PET myocardial flow reserve (MFR) has established diagnostic and prognostic
value. Technological advances have now enabled SPECT MFR quantification. We …

Test-Retest Precision of Myocardial Blood Flow Measurements With 99mTc-Tetrofosmin and Solid-State Detector Single Photon Emission Computed Tomography

RG Wells, I Radonjic, D Clackdoyle, J Do… - Circulation …, 2020 - Am Heart Assoc
Background: Measurement of myocardial blood flow (MBF) with single photon emission
computed tomography (SPECT) is feasible using cardiac cameras with solid-state detectors …

Patient motion correction for dynamic cardiac PET: Current status and challenges

Y Lu, C Liu - Journal of Nuclear Cardiology, 2020 - Springer
For dynamic cardiac PET of quantifying myocardial blood flow (MBF), patient motion is a
major factor that affects the ROI definition and absolute quantification accuracy. In a recent …

MR-based cardiac and respiratory motion correction of PET: application to static and dynamic cardiac 18F-FDG imaging

Y Petibon, T Sun, PK Han, C Ma… - Physics in Medicine …, 2019 - iopscience.iop.org
Motion of the myocardium deteriorates the quality and quantitative accuracy of cardiac PET
images. We present a method for MR-based cardiac and respiratory motion correction of …

Automated motion correction for myocardial blood Flow measurements and diagnostic performance of 82Rb PET myocardial perfusion imaging

K Kuronuma, CC Wei, A Singh, M Lemley… - Journal of Nuclear …, 2024 - Soc Nuclear Med
Motion correction (MC) affects myocardial blood flow (MBF) measurements in 82Rb PET
myocardial perfusion imaging (MPI); however, frame-by-frame manual MC of dynamic …