Why nature chose selenium

HJ Reich, RJ Hondal - ACS chemical biology, 2016 - ACS Publications
The authors were asked by the Editors of ACS Chemical Biology to write an article titled
“Why Nature Chose Selenium” for the occasion of the upcoming bicentennial of the …

Selenium and selenocysteine: roles in cancer, health, and development

DL Hatfield, PA Tsuji, BA Carlson… - Trends in biochemical …, 2014 - cell.com
The many biological and biomedical effects of selenium are relatively unknown outside the
selenium field. This fascinating element, initially described as a toxin, was subsequently …

[HTML][HTML] Functions of elements in soil microorganisms

M Hemkemeyer, SA Schwalb, S Heinze… - Microbiological …, 2021 - Elsevier
The soil microbial community fulfils various functions, such as nutrient cycling and carbon
(C) sequestration, therefore contributing to maintenance of soil fertility and mitigation of …

Evolutionary and structural insights into the multifaceted glutathione peroxidase (Gpx) superfamily

S Toppo, S Vanin, V Bosello… - Antioxidants & redox …, 2008 - liebertpub.com
Glutathione peroxidase (GPx) is a widespread protein superfamily found in many organisms
throughout all kingdoms of life. Although it was initially thought to use only glutathione as …

[HTML][HTML] The selenophosphate synthetase family: a review

B Manta, NE Makarova, M Mariotti - Free Radical Biology and Medicine, 2022 - Elsevier
Selenophosphate synthetases use selenium and ATP to synthesize selenophosphate. This
is required for biological utilization of selenium, most notably for the synthesis of the non …

Dynamic evolution of selenocysteine utilization in bacteria: a balance between selenoprotein loss and evolution of selenocysteine from redox active cysteine residues

Y Zhang, H Romero, G Salinas, VN Gladyshev - Genome biology, 2006 - Springer
Abstract Background Selenocysteine (Sec) is co-translationally inserted into protein in
response to UGA codons. It occurs in oxidoreductase active sites and often is catalytically …

Selenocysteine, pyrrolysine, and the unique energy metabolism of methanogenic archaea

M Rother, JA Krzycki - Archaea, 2010 - Wiley Online Library
Methanogenic archaea are a group of strictly anaerobic microorganisms characterized by
their strict dependence on the process of methanogenesis for energy conservation. Among …

Bioinformatics of selenoproteins

D Santesmasses, M Mariotti… - Antioxidants & redox …, 2020 - liebertpub.com
Significance: Bioinformatics has brought important insights into the field of selenium
research. The progress made in the development of computational tools in the last two …

General trends in trace element utilization revealed by comparative genomic analyses of Co, Cu, Mo, Ni, and Se

Y Zhang, VN Gladyshev - Journal of Biological Chemistry, 2010 - jbc.org
Trace elements are used by all organisms and provide proteins with unique coordination
and catalytic and electron transfer properties. Although many trace element-containing …

Comparative genomics of trace elements: emerging dynamic view of trace element utilization and function

Y Zhang, VN Gladyshev - Chemical reviews, 2009 - ACS Publications
Biological trace elements are needed in minute quantities forpropergrowth, development,
andphysiologyoforganisms. 1r3 These micronutrients include iron (Fe), zinc (Zn), copper …