The prevalence of child and adolescent obesity has plateaued at high levels in most high-
income countries and is increasing in many low-income and middle-income countries …

Mendelian randomization (MR) is a method of studying the causal effects of modifiable
exposures (ie, potential risk factors) on health, social, and economic outcomes using genetic …

Objective To evaluate whether body size in early life has an independent effect on risk of
disease in later life or whether its influence is mediated by body size in adulthood. Design …

In 2016, undernutrition, as manifested in childhood stunting, wasting, and underweight were
estimated to cause over 1.0 million deaths, 3.9% of years of life lost, and 3.8% of disability …

The genetic background of childhood body mass index (BMI), and the extent to which the
well-known associations of childhood BMI with adult diseases are explained by shared …

The causes of temporal fluctuations in adult traits are poorly understood. Here, we
investigate the genetic determinants of within-person trait variability of 8 repeatedly …

Obesity is a common complex trait that elevates the risk for various diseases, including type
2 diabetes and cardiovascular disease. A combination of environmental and genetic factors …

Obesity represents a major health burden to both developed and develo** countries.
Furthermore, the incidence of obesity is increasing in children. Obesity contributes …

Obesity is a heritable disease, characterised by excess adiposity that is measured by body
mass index (BMI). While over 1,000 genetic loci are associated with BMI, less is known …

Obesity rates have increased across all segments of society since the late 1970s, but the
reason behind population-level increases in body weight remains unclear. We used the …