Endogenous photosensitizers in human skin

EL Bastos, FH Quina, MS Baptista - Chemical Reviews, 2023 - ACS Publications
Endogenous photosensitizers play a critical role in both beneficial and harmful light-induced
transformations in biological systems. Understanding their mode of action is essential for …

Insights into molecular structure of pterins suitable for biomedical applications

AA Buglak, MA Kapitonova, YL Vechtomova… - International Journal of …, 2022 - mdpi.com
Pterins are an inseparable part of living organisms. Pterins participate in metabolic reactions
mostly as tetrahydropterins. Dihydropterins are usually intermediates of these reactions …

Photosensitized Oxidation of Free and Peptide Tryptophan to N-Formylkynurenine

JJ Farías, ML Dántola, AH Thomas - Chemical Research in …, 2024 - ACS Publications
The oxidation of proteins and, in particular, of tryptophan (Trp) residues leads to chemical
modifications that can affect the structure and function. The oxidative damage to proteins in …

Photo-induced protein modifications: A range of biological consequences and applications

CC Vera, CD Borsarelli - Biophysical Reviews, 2023 - Springer
Proteins are the most abundant biomolecules in living organisms and tissues and are also
present in many natural and processed foods and beverages, as well as in pharmaceuticals …

Silver cluster interactions with tyrosine: towards amino acid detection

AA Buglak, AI Kononov - International Journal of Molecular Sciences, 2022 - mdpi.com
Tyrosine (Tyr) is involved in the synthesis of neurotransmitters, catecholamines, thyroid
hormones, etc. Multiple pathologies are associated with impaired Tyr metabolism. Silver …

Enhancement of the Photosensitizing Properties of 6-Carboxypterin through Covalent Binding to the pH-Responsive and Biocompatible Poly (allylamine …

G Armijos-Capa, JS Tuninetti, AH Thomas… - … Applied Materials & …, 2023 - ACS Publications
A polymeric photosensitizer was synthesized through covalent attachment of the natural
photosensitizer 6-carboxypterin (Cap) to a poly (allylamine hydrochloride)(PAH) polymer …

Phototoxic Effects on Skin Biomolecules Induced by a Domestic Nail Polish Dryer Device

CA Ardila Padilla, M Vignoni, MP Serrano… - Chemical Research …, 2025 - ACS Publications
UVA radiation and visible light can lead to indirect damage to DNA, proteins, and lipids
through photosensitized reactions, where a molecule undergoes a photochemical alteration …

Photosensitized isomerization of resveratrol: Evaluation of energy and electron transfer pathways

JRN Recky, MG Tosato, AA Buglak, ML Dántola… - Free Radical Biology …, 2024 - Elsevier
Abstract Resveratrol (3, 5, 4′-trihydroxystilbene, RSV) is a natural stilbene synthetized as
trans-isomer in plants exposed to oxidative stress. In order to understand the mechanism …

Photochemical Processes of Cell DNA Damage by UV Radiation of Various Wavelengths: Biological Consequences

GY Fraikin, NS Belenikina, AB Rubin - Molecular Biology, 2024 - Springer
Photochemical reactions in cell DNA are induced in various organisms by solar UV radiation
and may lead to a series of biological responses to DNA damage, including apoptosis …

[HTML][HTML] Chemical modification of 5-hydroxytryptophan photoinduced by endogenous sensitizers present in skin

JJ Farías, P Lizondo-Aranda, MP Serrano… - Dyes and …, 2024 - Elsevier
Damage caused to biological targets through sunlight photosensitized reaction is of
paramount importance due to their potential effects on human health. In these processes, a …