[HTML][HTML] Future directions for the discovery of natural product-derived immunomodulating drugs: an IUPHAR positional review
Drug discovery from natural sources is going through a renaissance, having spent many
decades in the shadow of synthetic molecule drug discovery, despite the fact that natural …
decades in the shadow of synthetic molecule drug discovery, despite the fact that natural …
Biosynthesis and synthetic biology of psychoactive natural products
Psychoactive natural products play an integral role in the modern world. The tremendous
structural complexity displayed by such molecules confers diverse biological activities of …
structural complexity displayed by such molecules confers diverse biological activities of …
Plants and natural products with activity against various types of coronaviruses: a review with focus on SARS-CoV-2
COVID-19 is a pandemic disease caused by the SARS-CoV-2 virus, which is potentially fatal
for vulnerable individuals. Disease management represents a challenge for many countries …
for vulnerable individuals. Disease management represents a challenge for many countries …
Cytotoxic phytochemicals from the crude extract of Tetrapleura tetraptera fruits towards multi-factorial drug resistant cancer cells
Ethnopharmacological relevance Tetrapleura tetraptera is an African medicinal spice used
in traditional medicine to treat several ailments including cancer. Aim of the study The …
in traditional medicine to treat several ailments including cancer. Aim of the study The …
Medicinal plants and phytochemicals against multidrug-resistant tumor cells expressing ABCB1, ABCG2, or ABCB5: a synopsis of 2 decades
Multidrug resistance is a major factor causing the failure of cancer chemotherapy. Efflux
pumps of the ATP-binding cassette (ABC) transporter family expel a large array of diverse …
pumps of the ATP-binding cassette (ABC) transporter family expel a large array of diverse …
Natural products that changed society
SB Christensen - Biomedicines, 2021 - mdpi.com
Until the end of the 19th century all drugs were natural products or minerals. During the 19th
century chemists succeeded in isolating pure natural products such as quinine, morphine …
century chemists succeeded in isolating pure natural products such as quinine, morphine …
[HTML][HTML] Integration of phytochemicals and phytotherapy into cancer precision medicine
T Efferth, MEM Saeed, E Mirghani, A Alim, Z Yassin… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract Concepts of individualized therapy in the 1970s and 1980s attempted to develop
predictive in vitro tests for individual drug responsiveness without reaching clinical routine …
predictive in vitro tests for individual drug responsiveness without reaching clinical routine …
Mortiño (Vaccinium floribundum Kunth): An Underutilized Superplant from the Andes
SA Llivisaca-Contreras, F León-Tamariz… - Horticulturae, 2022 - mdpi.com
Mortiño is a member of the Ericaceae family native to the Andes that has been used by local
communities for centuries. This species has shown potential in the areas of medicine …
communities for centuries. This species has shown potential in the areas of medicine …
Production of marine-derived bioactive peptide molecules for industrial applications: A reverse engineering approach
AJ Surwase, NL Thakur - Biotechnology Advances, 2024 - Elsevier
This review examines a wide range of marine microbial-derived bioactive peptide
molecules, emphasizing the significance of reverse engineering in their production. The …
molecules, emphasizing the significance of reverse engineering in their production. The …
Advancing urban ethnopharmacology: A modern concept of sustainability, conservation and cross-cultural adaptations of medicinal plant lore in the urban …
The discipline 'urban ethnopharmacology'emerged as a collection of traditional knowledge,
ancient civilizations, history and folklore being circulated since generations, usage of …
ancient civilizations, history and folklore being circulated since generations, usage of …