Bladder cancer

L Dyrskjøt, DE Hansel, JA Efstathiou… - Nature reviews Disease …, 2023 - nature.com
Bladder cancer is a global health issue with sex differences in incidence and prognosis.
Bladder cancer has distinct molecular subtypes with multiple pathogenic pathways …

[HTML][HTML] Epidemiology of bladder cancer in 2023: a systematic review of risk factors

I Jubber, S Ong, L Bukavina, PC Black, E Compérat… - European urology, 2023 - Elsevier
Context Bladder cancer (BC) is common worldwide and poses a significant public health
challenge. External risk factors and the wider exposome (totality of exposure from external …

Regulation of cisplatin resistance in bladder cancer by epigenetic mechanisms

F Li, Z Zheng, W Chen, D Li, H Zhang, Y Zhu… - Drug Resistance …, 2023 - Elsevier
Bladder cancer is one of the most common malignancies in the world. Cisplatin is one of the
most potent and widely used anticancer drugs and has been employed in several …

Radical cystectomy versus trimodality therapy for muscle-invasive bladder cancer: a multi-institutional propensity score matched and weighted analysis

AR Zlotta, LK Ballas, A Niemierko, K Lajkosz… - The lancet …, 2023 - thelancet.com
Background Previous randomised controlled trials comparing bladder preservation with
radical cystectomy for muscle-invasive bladder cancer closed due to insufficient accrual …

miRNAs role in bladder cancer pathogenesis and targeted therapy: signaling pathways interplay–a review

HA El-Mahdy, EGE Elsakka, AA El-Husseiny… - … -Research and Practice, 2023 - Elsevier
Bladder cancer (BC) is the 11th most popular cancer in females and 4th in males. A lot of
efforts have been exerted to improve BC patients' care. Besides, new approaches have …

From LncRNA to metastasis: The MALAT1-EMT axis in cancer progression

R Thapa, O Afzal, M Afzal, G Gupta, AA Bhat… - … -Research and Practice, 2024 - Elsevier
Cancer is a complex disease that causes abnormal genetic changes and unchecked cellular
growth. It also causes a disruption in the normal regulatory processes that leads to the …

A Hybrid Nanoadjuvant Simultaneously Depresses PD‐L1/TGF‐β1 and Activates cGAS‐STING Pathway to Overcome Radio‐Immunotherapy Resistance

L Yi, X Jiang, Z Zhou, W **ong, F Xue, Y Liu… - Advanced …, 2024 - Wiley Online Library
Currently, certain cancer patients exhibit resistance to radiotherapy due to reduced DNA
damage under hypoxic conditions and acquired immune tolerance triggered by transforming …

[HTML][HTML] European cancer mortality predictions for the year 2024 with focus on colorectal cancer

C Santucci, S Mignozzi, M Malvezzi, P Boffetta… - Annals of …, 2024 - Elsevier
Background We predicted cancer mortality figures for 2024 for the European Union (EU), its
five most populous countries, and the UK. We focused on mortality from colorectal cancer …

Targeting DNA damage and repair machinery via delivering WEE1 inhibitor and platinum (IV) prodrugs to stimulate STING pathway for maximizing chemo …

W Wang, F Yang, L Zhang, M Wang, L Yin… - Advanced …, 2024 - Wiley Online Library
Both cisplatin‐based chemotherapy and immune checkpoint blockers (ICBs)‐based
immunotherapy are the first‐line treatments for patients with advanced bladder cancer …

Integrated multiomics analysis and machine learning refine molecular subtypes and prognosis for muscle-invasive urothelial cancer

G Chu, X Ji, Y Wang, H Niu - Molecular Therapy-Nucleic Acids, 2023 - cell.com
Muscle-invasive urothelial cancer (MUC), characterized by high aggressiveness and
significant heterogeneity, is currently lacking highly precise individualized treatment options …