CO 2-fixation into cyclic and polymeric carbonates: principles and applications

AJ Kamphuis, F Picchioni, PP Pescarmona - Green chemistry, 2019 - pubs.rsc.org
The reaction between carbon dioxide and epoxides is an attractive pathway for CO2-
utilisation as it can lead to the formation of two different, yet valuable, products: cyclic and …

Emerging applications of carbon nanohoops

EJ Leonhardt, R Jasti - Nature Reviews Chemistry, 2019 - nature.com
A cycloparaphenylene can be thought of as the shortest possible cross section of an
armchair carbon nanotube. Although envisioned decades ago, these molecules—also …

Poly (trimethylene carbonate)-based polymers engineered for biodegradable functional biomaterials

K Fukushima - Biomaterials science, 2016 - pubs.rsc.org
Aliphatic polycarbonates have drawn attention as biodegradable polymers that can be
applied to a broad range of resorbable medical devices. In particular, poly (trimethylene …

Multicellular tumor spheroids (MCTS) as a 3D in vitro evaluation tool of nanoparticles

H Lu, MH Stenzel - Small, 2018 - Wiley Online Library
Multicellular tumor spheroid models (MCTS) are often coined as 3D in vitro models that can
mimic the microenvironment of tissues. MCTS have gained increasing interest in the nano …

Smart transformable nanomedicines for cancer therapy

Y Wang, S Li, X Wang, Q Chen, Z He, C Luo, J Sun - Biomaterials, 2021 - Elsevier
Despite that great progression has been made in nanoparticulate drug delivery systems
(nano-DDS), multiple drug delivery dilemmas still impair the delivery efficiency of …

Multicellular tumor spheroids: a relevant 3D model for the in vitro preclinical investigation of polymer nanomedicines

G Lazzari, P Couvreur, S Mura - Polymer Chemistry, 2017 - pubs.rsc.org
The application of nanotechnology to medicine, usually termed nanomedicine, has given a
crucial impulse to the design of various drug-loaded nanocarriers driven by the aim to …

Paclitaxel loaded liposomes decorated with a multifunctional tandem peptide for glioma targeting

Y Liu, R Ran, J Chen, Q Kuang, J Tang, L Mei, Q Zhang… - Biomaterials, 2014 - Elsevier
The treatment of glioma is a great challenge because of the existence of the blood-brain
barrier (BBB). In order to reduce toxicity to the normal brain tissue and achieve efficient …

Nanoparticles of 2-deoxy-D-glucose functionalized poly (ethylene glycol)-co-poly (trimethylene carbonate) for dual-targeted drug delivery in glioma treatment

X Jiang, H **n, Q Ren, J Gu, L Zhu, F Du, C Feng, Y **e… - Biomaterials, 2014 - Elsevier
Based on the facilitative glucose transporter (GLUT) over-expression on both blood–brain
barrier (BBB) and glioma cells, 2-deoxy-d-glucose modified poly (ethylene glycol)-co-poly …

The binding site barrier elicited by tumor-associated fibroblasts interferes disposition of nanoparticles in stroma-vessel type tumors

L Miao, JM Newby, CM Lin, L Zhang, F Xu, WY Kim… - ACS …, 2016 - ACS Publications
The binding site barrier (BSB) was originally proposed to describe the binding behavior of
antibodies to cells peripheral to blood vessels, preventing their further penetration into the …

Particle targeting in complex biological media

Q Dai, N Bertleff‐Zieschang… - Advanced …, 2018 - Wiley Online Library
Over the past few decades, nanoengineered particles have gained increasing interest for
applications in the biomedical realm, including diagnosis, imaging, and therapy. When …