Hypertension is the most frequent medical complication occurring during pregnancy. In this
chapter, we aim to address the genetic contribution to these disorders, with specific focus on …

Citation Thaxton JE, Sharma S. Interleukin‐10: a multi‐faceted agent of pregnancy. Am J
Reprod Immunol 2010 It is widely accepted that pregnancy constitutes a unique …

Background Preeclampsia is a severe complication of pregnancy characterized by an
excessive maternal systemic inflammatory response with activation of both the innate and …

В доступной форме в книге изложены основные события, произошедшие в
медицинской генетике и в молекулярной медицине после расшифровки генома …

BACKGROUND Pre-eclampsia has a clear familial component, suggesting that the condition
may be partly attributable to genetic susceptibility. The search for susceptibility genes has …

Preeclampsia is specific to pregnancy and is still a leading cause of maternal and perinatal
mortality and morbidity, affecting about 3% of women, but the underlying pathogenetic …

Although preeclampsia causes high maternal/fetal morbidity and mortality, the etiology of
this multi-system disorder still remains to be elucidated. Herein, we have characterized the …

The relevance of gene polymorphisms in the development of unexplained recurrent
spontaneous abortion is still unclear. Cytokines, angiogenic mediators, and hormones are …

Background: Preeclampsia (PE) is a syndromic disorder that affects 2% to 8% of
pregnancies and is diagnosed principally when hypertension appears in the second-d half …

Inflammation may play a major role in the pathogenesis of preeclampsia (PE). In this meta-
analysis, we determined whether maternal polymorphisms and serum concentrations of …