Recent progress on the underlying biological mechanisms of healthy longevity has
propelled the field from elucidating genetic modification of healthy longevity hallmarks to …

The metformin molecule dates back to over a century, but its clinical use started in the '50 s.
Since then, its use in diabetics has grown constantly, with over 150 million users today. The …

Cardiovascular diseases (CVD) cause significant global morbidity, mortality and public
health burden annually. CVD alters richness, diversity, and composition of Gut microbiota …

Background/Objectives. The comorbidity of osteoarthritis and type 2 diabetes mellitus poses
a complex clinical challenge, complicating patient management due to overlap** …

Diabetes mellitus (DM) and osteoarthritis (OA) are prevalent chronic conditions with shared
pathophysiological links, including inflammation and metabolic dysregulation. This study …

This review article explores the potential of metformin, a medication commonly used for type
2 diabetes, as an antiviral and anti-inflammatory agent in the context of coronavirus disease …

Metformin, one of the most frequently used oral glucose-lowering drugs (GLDs), is
associated with the occurrence of gastrointestinal (GI) adverse events in approximately 20 …

Background The comorbidity of chronic pancreatitis (CP) in patients with osteoarthritis (OA)
is insufficiently studied, and the reciprocal impact of these conditions remains poorly …

COVID-19 remains a significant global concern, particularly for individuals with type 2
diabetes who face an elevated risk of hospitalization and mortality. Metformin, a primary …

Gestational diabetes mellitus (GDM) is a complex metabolic condition during pregnancy with
an intricate link to gut microbiota alterations. Throughout gestation, notable shifts in the gut …