Nonsteroidal anti-inflammatory drugs: adverse effects and their prevention

HE Vonkeman, MAFJ van de Laar - Seminars in arthritis and rheumatism, 2010 - Elsevier
OBJECTIVES: To discuss nonsteroidal anti-inflammatory drugs (NSAIDs), their history,
development, mode of action, toxicities, strategies for the prevention of toxicity, and future …

Gastroprotective effect of zingerone on ethanol-induced gastric ulcers in rats

N Sistani Karampour, A Arzi, A Rezaie… - Medicina, 2019 - mdpi.com
Background and objectives: Zingerone is an ingredient of ginger (Zingiber officinale) with
different pharmacological activities. Several studies have investigated the effect of zingerone …

Cost-effectiveness of screening for atrial fibrillation in primary care with a handheld, single-lead electrocardiogram device in the Netherlands

MS Jacobs, F Kaasenbrood, MJ Postma… - Ep …, 2018 - academic.oup.com
Aims Atrial fibrillation (AF) is the most common arrhythmia and prevalence increases with
age. Patients with AF have a high risk of stroke, and screening for AF is recommended in all …

Amelioration of Ethanol-Induced Gastric Ulcers in Rats Pretreated with Phycobiliproteins of Arthrospira (Spirulina) Maxima

O Guzmán-Gómez, RV García-Rodríguez… - Nutrients, 2018 - mdpi.com
Phycobiliproteins of Arthrospira (Spirulina) maxima have attracted attention because of their
potential therapeutic antioxidant properties. The aim of this study was to assess the possible …

Preventing the gastrointestinal adverse effects of nonsteroidal anti-inflammatory drugs: from risk factor identification to risk factor intervention

M Bardou, AN Barkun - Joint Bone Spine, 2010 - Elsevier
Nonsteroidal anti-inflammatory drugs (NSAIDs) have huge prescription volumes, for two
main reasons: the aging of the population is increasing the prevalence of diseases that …

[HTML][HTML] Antiulcerogenic activity of Scutia buxifolia on gastric ulcers induced by ethanol in rats

AA Boligon, RB De Freitas, TF de Brum… - … Pharmaceutica Sinica B, 2014 - Elsevier
Gastric ulcers affect many people around the world and their development is a result of the
imbalance between aggressive and protective factors in the gastric mucosa. Scutia buxifolia …

The effect of a minor constituent of essential oil from Citrus aurantium: The role of β-myrcene in preventing peptic ulcer disease

F Bonamin, TM Moraes, RC Dos Santos… - Chemico-biological …, 2014 - Elsevier
The monoterpene β-myrcene has been widely used in cosmetics, food and beverages, and
it is normally found in essential oil from citrus fruit. The aim of this study was to investigate …

Protective effects of pogostone from Pogostemonis Herba against ethanol-induced gastric ulcer in rats

H Chen, H Liao, Y Liu, Y Zheng, X Wu, Z Su, X Zhang… - Fitoterapia, 2015 - Elsevier
We examined the protective effect of pogostone (PO), a chemical constituent isolated from
Pogostemonis Herba, on the ethanol-induced gastric ulcer in rats. Administration of PO at …

Management of patients on nonsteroidal anti-inflammatory drugs: a clinical practice recommendation from the First International Working Party on Gastrointestinal and …

FKL Chan, NS Abraham, JM Scheiman… - Official journal of the …, 2008 - journals.lww.com
BACKGROUND Prescribing nonsteroidal antiinflammatory drugs (NSAIDs) is challenging
because physicians have to consider gastrointestinal (GI) and cardiovascular (CV) safety …

Evaluation of Ulcer Protective Activity of Morus alba L. Extract‐Loaded Chitosan Microspheres in Ethanol‐Induced Ulcer in Rat Model

S Garg, RK Singla, MM Rahman… - Evidence‐Based …, 2022 - Wiley Online Library
Due to an unhealthy lifestyle, gastric ulcers have become a very common disease these
days. Moreover, the side effects linked with the prolonged use of conventional treatments …