Tumor metastasis is a major contributor to the death of cancer patients. It is driven not only
by the intrinsic alterations in tumor cells, but also by the implicated cross-talk between …

Cancer immunotherapy has emerged as a novel cancer treatment, although recent
immunotherapy trials have produced suboptimal outcomes, with durable responses seen …

Macrophages have protective roles in immunity to pathogens, tissue development,
homeostasis and repair following damage. Maladaptive immunity and inflammation provoke …

Monocytes are considered to be precursor cells of the mononuclear phagocytic system, and
macrophages are one of the leading members of this cellular system. Macrophages play …

Abstract Changes in glycosylation during tumour progression are a key hallmark of cancer.
One of the glycan moieties generally overexpressed in cancer are sialic acids, which can …

Tumor associated macrophages (TAMs) are the most frequent immune cells within tumor
microenvironment (TME). There is growing evidence that TAMs are involved in tumor …

Resistance to cancer therapy is a major barrier to cancer management. Conventional views
have proposed that acquisition of resistance may result from genetic mutations. However …

During placentation invasive extravillous trophoblasts (EVTs) migrate into the maternal
uterus and modify its vessels. In particular, remodeling of the spiral arteries by EVTs is …

Tumor‐associated macrophages (TAMs) are one of the most abundant cell types in
colorectal cancer (CRC) tumor microenvironment (TME). Recent studies observed …

Systemic and local chronic inflammation might enhance the risk of pancreatic ductal
adenocarcinoma (PDAC), and PDAC-associated inflammatory infiltrate in the tumor …