The role of trained immunity in COVID-19: Lessons for the next pandemic

MG Netea, A Ziogas, CS Benn… - Cell Host & Microbe, 2023‏ - cell.com
Trained immunity is a long-term increase in responsiveness of innate immune cells, induced
by certain infections and vaccines. During the last 3 years of the COVID-19 pandemic …

B cells in perivascular and peribronchiolar granuloma-associated lymphoid tissue and B-cell signatures identify asymptomatic Mycobacterium tuberculosis lung …

D Koyuncu, T Tavolara, DM Gatti, AC Gower… - Infection and …, 2024‏ - journals.asm.org
Because most humans resist Mycobacterium tuberculosis infection, there is a paucity of lung
samples to study. To address this gap, we infected Diversity Outbred mice with M …

Perivascular and peribronchiolar granuloma-associated lymphoid tissue and B-cell gene expression pathways identify asymptomatic Mycobacterium tuberculosis …

D Koyuncu, T Tavolara, DM Gatti, AC Gower… - bioRxiv, 2023‏ - biorxiv.org
Humans are highly genetically diverse, and most are resistant to Mycobacterium
tuberculosis. However, lung tissue from genetically resistant humans is not readily available …