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[HTML][HTML] Challenge in the discovery of new drugs: antimicrobial peptides against WHO-list of critical and high-priority bacteria
Bacterial resistance has intensified in recent years due to the uncontrolled use of
conventional drugs, and new bacterial strains with multiple resistance have been reported …
conventional drugs, and new bacterial strains with multiple resistance have been reported …
Amidation of glutamate residues in mycobacterial peptidoglycan is essential for cell wall cross-linking
Introduction Mycobacteria assemble a complex cell wall with cross-linked peptidoglycan
(PG) which plays an essential role in maintenance of cell wall integrity and tolerance to …
(PG) which plays an essential role in maintenance of cell wall integrity and tolerance to …
CRISPRi-mediated characterization of novel anti-tuberculosis targets: Mycobacterial peptidoglycan modifications promote beta-lactam resistance and intracellular …
The lack of effective therapeutics against emerging multi-drug resistant strains of
Mycobacterium tuberculosis (Mtb) prompts the identification of novel anti-tuberculosis …
Mycobacterium tuberculosis (Mtb) prompts the identification of novel anti-tuberculosis …
A modified BCG with depletion of enzymes associated with peptidoglycan amidation induces enhanced protection against tuberculosis in mice
Mechanisms by which Mycobacterium tuberculosis (Mtb) evades pathogen recognition
receptor activation during infection may offer insights for the development of improved …
receptor activation during infection may offer insights for the development of improved …
Identification and characterization of archaeal pseudomurein biosynthesis genes through pangenomics
The peptidoglycan (PG, or murein) is a mesh-like structure, which is made of glycan
polymers connected by short peptides and surrounds the cell membrane of nearly all …
polymers connected by short peptides and surrounds the cell membrane of nearly all …
The mutation rate of rpoB gene showed an upward trend with the increase of MIRU10, MIRU39 and QUB4156 repetitive number
F Su, L Cao, X Ren, J Hu, G Tavengana, H Wu, Y Zhou… - BMC genomics, 2023 - Springer
Background Mycobacterial interspersed repetitive unit-variable number tandem repeat
(MIRU-VNTR) is a frequently used ty** method for identifying the Bei**g genotype of …
(MIRU-VNTR) is a frequently used ty** method for identifying the Bei**g genotype of …
Origin and Evolution of Pseudomurein Biosynthetic Gene Clusters
The peptidoglycan (PG; or murein) is a mesh-like structure, which is made of glycan
polymers connected by short peptides and surrounds the cell membrane of nearly all …
polymers connected by short peptides and surrounds the cell membrane of nearly all …
Investigating the role of CwlM interaction with MviN and peptidoglycan in mycobacterial growth and stress response
A Alrajhi - 2024 - figshare.le.ac.uk
Mycobacterium tuberculosis is one of the major disease-causing agents worldwide; it claims
over one million lives annually. The complex lipid rich cell wall is a critical component that …
over one million lives annually. The complex lipid rich cell wall is a critical component that …
[PDF][PDF] Molecular mechanisms of drug synergy and persistence in Mycobacterium tuberculosis
Y Xu - 2023 - openresearch.surrey.ac.uk
Molecular mechanisms of drug synergy and persistence in Mycobacterium tuberculosis Page 1
Molecular mechanisms of drug synergy and persistence in Mycobacterium tuberculosis by Ye …
Molecular mechanisms of drug synergy and persistence in Mycobacterium tuberculosis by Ye …
[PDF][PDF] Peptidoglycan amidation enzymes in Mycobacterium tuberculosis are new drug targets for Tuberculosis treatment and development of a novel TB vaccine
MT Shaku - 2023 - wiredspace.wits.ac.za
Mycobacterium tuberculosis (Mtb) is the causative agent of Tuberculosis (TB), a
communicable disease that remains the leading cause of death from an infectious disease …
communicable disease that remains the leading cause of death from an infectious disease …