Binding of the Helicobacter pylori OipA causes apoptosis of host cells via modulation of Bax/Bcl-2 levels

O Teymournejad, AM Mobarez, ZM Hassan… - Scientific reports, 2017 - nature.com
The H. pylori outer inflammatory protein A (OipA) is an outer membrane protein that
contributes to gastric inflammation. OipA is believed to affect intra-cellular signalling and …

In silico design of Mycobacterium tuberculosis epitope ensemble vaccines

P Shah, J Mistry, PA Reche, D Gatherer… - Molecular immunology, 2018 - Elsevier
Effective control of Mycobacterium tuberculosis is a global necessity. In 2015, tuberculosis
(TB) caused more deaths than HIV. Considering the increasing prevalence of multi-drug …

[HTML][HTML] Protection of BALB/c mice against pathogenic Brucella abortus and Brucella melitensis by vaccination with recombinant Omp16

H Alizadeh, M Dezfulian, M Rahnema… - Iranian Journal of …, 2019 - ncbi.nlm.nih.gov
Objective (s): Prevention of the globally spread zoonotic infection, brucellosis which affects
an extensive range of hosts is still challenging researchers. There are no approved vaccines …

Recombinant Omp2b antigen-based ELISA is an efficient tool for specific serodiagnosis of animal brucellosis

M Vatankhah, N Beheshti, S Mirkalantari… - Brazilian Journal of …, 2019 - Springer
Control of brucellosis as a worldwide zoonotic disease is based on vaccination of animals
and diagnosis of infected cases to be eradicated. Accurate and rapid detection of infected …

Ag85B with c-di-AMP as mucosal adjuvant showed immunotherapeutic effects on persistent Mycobacterium tuberculosis infection in mice

X Liang, R Cui, X Li, H Ning, J Kang, Y Lu… - Brazilian Journal of …, 2024 - SciELO Brasil
Tuberculosis (TB), caused by Mycobacterium tuberculosis, remains the leading cause of
mortality by a single infectious agent in the world. M. tuberculosis infection could also result …

Characterization of Sortase A in Lactobacillus Acidophilus ATCC 4356 Involved in Adherence to Intestinal Cells

Z Wu, J Wu, F Lang, Z Cai, X Zeng, Y Guo… - Future …, 2020 - Taylor & Francis
Aim: Confirmation of the enzymatic activity of Class A sortase (SrtA) in probiotic strain
Lactobacillus acidophilus associated with the adhesion properties. Materials & methods …

[HTML][HTML] Alpha alumina nanoparticle conjugation to cysteine peptidase A and B: an efficient method for autophagy induction

F Beyzay, AZ Hosseini, S Soudi - Avicenna Journal of Medical …, 2017 - ncbi.nlm.nih.gov
Background: Autophagy as a cellular pathway facilitates several immune responses against
infection. It also eliminates invading pathogens through transferring content between the …

[HTML][HTML] Cloning, expression, and purification of Pseudomonas aeruginosa flagellin, and characterization of the elicited anti-flagellin antibody

B Behrouz, N Amirmozafari… - Iranian Red Crescent …, 2016 - ncbi.nlm.nih.gov
Background: Pseudomonas aeruginosa is an important opportunistic human pathogen that
causes serious infections in immunocompromised hosts. The single polar flagellum is an …

Protection of mice against Staphylococcus aureus infection by a recombinant protein ClfA–IsdB–Hlg as a vaccine candidate

S Delfani, A Mohabati Mobarez… - Medical microbiology …, 2016 - Springer
Staphylococcus aureus is one of the most important causes of nosocomial infections. An
effective vaccine to prevent S. aureus infections is urgently required due to the dramatic …

Induction of protective immunity by recombinant peptidoglycan associated lipoprotein (rPAL) protein of Legionella pneumophila in a BALB/c mouse model

AM Mobarez, RA Rajabi, AH Salmanian… - Microbial …, 2019 - Elsevier
Legionella pneumophila causes a severe form of pneumonia known as Legionnaires'
disease especially in patients with impaired cellular immune response. In order to prevent …