The risk factors influencing the natural course of chronic kidney disease (CKD) are complex
and heterogeneous, and few systematic reviews to date have focused on this issue. The aim …

Anderson–Fabry disease (AFD) is a rare disease with an incidenceof approximately 1:
117,000 male births. Lysosomal accumulation of globotriaosylceramide (Gb3) is the element …

Context Chronic kidney disease (CKD) is common. Kidney disease severity can be
classified by estimated glomerular filtration rate (GFR) and albuminuria, but more accurate …

Background Few cohort studies have focused on risk factors for end-stage renal disease
(ESRD). This investigation evaluated the prognostic value of several potential novel risk …

Progressive CKD is generally detected at a late stage by a sustained decline in eGFR and/or
the presence of significant albuminuria. With the aim of early and improved risk stratification …

Background Population mean GFR is lower in older age, but it is unknown whether healthy
aging is associated with preserved rather than lower GFR in some individuals. Methods We …

BP is an important determinant of kidney disease among patients with diabetes. The
recommended thresholds to initiate treatment to lower BP are 130/80 and 125/75 mmHg for …

Background Identification of risk factors for development of chronic kidney disease (CKD) in
cats may aid in its earlier detection. Hypothesis/objectives Evaluation of clinical and …

Background There are a growing number of studies on ethnic differences in progression and
mortality for pre-dialysis chronic kidney disease (CKD), but this literature has yet to be …

Chronic kidney disease (CKD) is often accompanied with colon mucosal barrier damage
and gut microbiota disturbance, which strongly associate with up-regulated inflammation …