Giant vesicles as cell models
SF Fenz, K Sengupta - Integrative Biology, 2012 - academic.oup.com
Tremendous progress has been made in recent years in understanding the working of the
living cell, including its micro-anatomy, signalling networks, and regulation of genes …
living cell, including its micro-anatomy, signalling networks, and regulation of genes …
Physics of cell adhesion: some lessons from cell-mimetic systems
E Sackmann, AS Smith - Soft matter, 2014 - pubs.rsc.org
Cell adhesion is a paradigm of the ubiquitous interplay of cell signalling, modulation of
material properties and biological functions of cells. It is controlled by competition of short …
material properties and biological functions of cells. It is controlled by competition of short …
Measuring shape fluctuations in biological membranes
C Monzel, K Sengupta - Journal of Physics D: Applied Physics, 2016 - iopscience.iop.org
Shape fluctuations of lipid membranes have intrigued cell biologists and physicists alike. In
the cellular context, their origin—thermal or active—and their physiological significance are …
the cellular context, their origin—thermal or active—and their physiological significance are …
Membrane fluctuations mediate lateral interaction between cadherin bonds
The integrity of living tissues is maintained by adhesion domains of trans-bonds formed
between cadherin proteins residing on opposing membranes of neighbouring cells. These …
between cadherin proteins residing on opposing membranes of neighbouring cells. These …
Measuring fast stochastic displacements of bio-membranes with dynamic optical displacement spectroscopy
Stochastic displacements or fluctuations of biological membranes are increasingly
recognized as an important aspect of many physiological processes, but hitherto their …
recognized as an important aspect of many physiological processes, but hitherto their …
Mechanisms of motor-independent membrane remodeling driven by dynamic microtubules
Microtubule-dependent organization of membranous organelles occurs through motor-
based pulling and by coupling microtubule dynamics to membrane remodeling. For …
based pulling and by coupling microtubule dynamics to membrane remodeling. For …
Ligand-mediated friction determines morphodynamics of spreading T cells
P Dillard, R Varma, K Sengupta, L Limozin - Biophysical journal, 2014 - cell.com
Spreading of T cells on antigen presenting cells is a crucial initial step in immune response.
Spreading occurs through rapid morphological changes concomitant with the reorganization …
Spreading occurs through rapid morphological changes concomitant with the reorganization …
Monte Carlo study of the frame, fluctuation and internal tensions of fluctuating membranes with fixed area
Three types of surface tensions can be defined for lipid membranes: the internal tension, σ,
conjugated to the real membrane area in the Hamiltonian, the mechanical frame tension, τ …
conjugated to the real membrane area in the Hamiltonian, the mechanical frame tension, τ …
Inter-membrane adhesion mediated by mobile linkers: effect of receptor shortage
Giant unilamellar vesicles (GUVs) adhering to supported bilayers were used as a model
system to mimic ligand–receptor mediated cell-cell adhesion. We present the effect of …
system to mimic ligand–receptor mediated cell-cell adhesion. We present the effect of …
Cantilevered-capillary force apparatus for measuring multiphase fluid interactions
A new instrument is presented for investigating interactions between individual colloidal
particles, emulsion droplets, foam bubbles, and other particle–particle or particle–surface …
particles, emulsion droplets, foam bubbles, and other particle–particle or particle–surface …