Giant vesicles as cell models

SF Fenz, K Sengupta - Integrative Biology, 2012 - academic.oup.com
Tremendous progress has been made in recent years in understanding the working of the
living cell, including its micro-anatomy, signalling networks, and regulation of genes …

Physics of cell adhesion: some lessons from cell-mimetic systems

E Sackmann, AS Smith - Soft matter, 2014 - pubs.rsc.org
Cell adhesion is a paradigm of the ubiquitous interplay of cell signalling, modulation of
material properties and biological functions of cells. It is controlled by competition of short …

Measuring shape fluctuations in biological membranes

C Monzel, K Sengupta - Journal of Physics D: Applied Physics, 2016 - iopscience.iop.org
Shape fluctuations of lipid membranes have intrigued cell biologists and physicists alike. In
the cellular context, their origin—thermal or active—and their physiological significance are …

Membrane fluctuations mediate lateral interaction between cadherin bonds

SF Fenz, T Bihr, D Schmidt, R Merkel, U Seifert… - Nature physics, 2017 - nature.com
The integrity of living tissues is maintained by adhesion domains of trans-bonds formed
between cadherin proteins residing on opposing membranes of neighbouring cells. These …

Measuring fast stochastic displacements of bio-membranes with dynamic optical displacement spectroscopy

C Monzel, D Schmidt, C Kleusch… - Nature …, 2015 - nature.com
Stochastic displacements or fluctuations of biological membranes are increasingly
recognized as an important aspect of many physiological processes, but hitherto their …

Mechanisms of motor-independent membrane remodeling driven by dynamic microtubules

R Rodríguez-García, VA Volkov, CY Chen… - Current Biology, 2020 - cell.com
Microtubule-dependent organization of membranous organelles occurs through motor-
based pulling and by coupling microtubule dynamics to membrane remodeling. For …

Ligand-mediated friction determines morphodynamics of spreading T cells

P Dillard, R Varma, K Sengupta, L Limozin - Biophysical journal, 2014 - cell.com
Spreading of T cells on antigen presenting cells is a crucial initial step in immune response.
Spreading occurs through rapid morphological changes concomitant with the reorganization …

Monte Carlo study of the frame, fluctuation and internal tensions of fluctuating membranes with fixed area

H Shiba, H Noguchi, JB Fournier - Soft Matter, 2016 - pubs.rsc.org
Three types of surface tensions can be defined for lipid membranes: the internal tension, σ,
conjugated to the real membrane area in the Hamiltonian, the mechanical frame tension, τ …

Inter-membrane adhesion mediated by mobile linkers: effect of receptor shortage

SF Fenz, AS Smith, R Merkel, K Sengupta - Soft Matter, 2011 - pubs.rsc.org
Giant unilamellar vesicles (GUVs) adhering to supported bilayers were used as a model
system to mimic ligand–receptor mediated cell-cell adhesion. We present the effect of …

Cantilevered-capillary force apparatus for measuring multiphase fluid interactions

JM Frostad, MC Collins, LG Leal - Langmuir, 2013 - ACS Publications
A new instrument is presented for investigating interactions between individual colloidal
particles, emulsion droplets, foam bubbles, and other particle–particle or particle–surface …