Rhodococcus equi: the many facets of a pathogenic actinomycete

JA Vázquez-Boland, S Giguère, A Hapeshi… - Veterinary …, 2013 - Elsevier
Rhodococcus equi is a soil-dwelling pathogenic actinomycete that causes pulmonary and
extrapulmonary pyogranulomatous infections in a variety of animal species and people …

Rhodococcus equi foal pneumonia: Update on epidemiology, immunity, treatment and prevention

AI Bordin, L Huber, MG Sanz… - Equine veterinary …, 2022 - Wiley Online Library
Pneumonia in foals caused by the bacterium Rhodococcus equi has a worldwide
distribution and is a common cause of disease and death for foals. The purpose of this …

Diagnosis, Treatment, Control, and Prevention of Infections Caused by Rhodococcus equi in Foals

S Giguère, ND Cohen, M Keith Chaffin… - Journal of veterinary …, 2011 - Wiley Online Library
Rhodococcus equi, a Gram‐positive facultative intracellular pathogen, is one of the most
common causes of pneumonia in foals. Although R. equi can be cultured from the …

Disorders of the gastrointestinal system

LC Sanchez - Equine internal medicine, 2017 - pmc.ncbi.nlm.nih.gov
* The editors and authors acknowledge and appreciate the contributions of Samuel L.
Jones, Katharina I. Lohmann, Michelle Henry Barton, Laura Javsicas, Anthony T. Blikslager …

Retrospective Comparison of Azithromycin, Clarithromycin, and Erythromycin for the Treatment of Foals with Rhodococcus equi Pneumonia

S Giguére, S Jacks, GD Roberts… - Journal of Veterinary …, 2004 - Wiley Online Library
The objective of this retrospective study was to compare the efficacy of azithromycin‐
rifampin, clarithromycin‐rifampin, and erythromycin‐rifampin for the treatment of pneumonia …

In Vitro Susceptibilities of Rhodococcus equi and Other Common Equine Pathogens to Azithromycin, Clarithromycin, and 20 Other Antimicrobials

SS Jacks, S Giguère, A Nguyen - Antimicrobial agents and …, 2003 - Am Soc Microbiol
The objective of this study was to determine in vitro activities of azithromycin (AZM),
clarithromycin (CLR), and 20 other antimicrobial agents against Rhodococcus equi and …

Pharmacokinetics and tissue distribution of doxycycline after oral administration of single and multiple doses in horses

JL Davis, JH Salmon, MG Papich - American journal of …, 2006 - Am Vet Med Assoc
Objective—To determine pharmacokinetics, safety, and penetration into interstitial fluid (ISF),
polymorphonuclear leukocytes (PMNLs), and aqueous humor of doxycycline after oral …

Treatment of infections caused by Rhodococcus equi

S Giguère - Veterinary Clinics: Equine Practice, 2017 - vetequine.theclinics.com
Pneumonia is the leading cause of disease and death in foals in some states 1 and ranks
third as a cause of morbidity and second (after a combined category of trauma, injury, and …

Chemoprophylactic effects of azithromycin against Rhodococcus equi–induced pneumonia among foals at equine breeding farms with endemic infections

MK Chaffin, ND Cohen… - Journal of the American …, 2008 - Am Vet Med Assoc
Objective—To determine the effect of azithromycin chemoprophylaxis on the cumulative
incidence of pneumonia caused by Rhodococcus equi, age at onset of pneumonia, and …

Macrolides, azalides, and ketolides

S Giguère - Antimicrobial therapy in veterinary medicine, 2013 - Wiley Online Library
The macrolides exhibit broad distribution in tissues and, in the case of some of the newer
drugs, prolonged half‐lives. The macrolides are also known for their intracellular …