Ethnopharmacological relevance Network pharmacology is a new discipline based on
systems biology theory, biological system network analysis, and multi-target drug molecule …

The research field of systems biology has greatly advanced and, as a result, the concept of
network pharmacology has been developed. This advancement, in turn, has shifted the …

Arrhythmogenic cardiomyopathy (ACM) is an arrhythmogenic disorder of the myocardium
not secondary to ischemic, hypertensive, or valvular heart disease. ACM incorporates a …

Since the early days of the genome era, the scientific community has relied on a single
'reference'genome for each species, which is used as the basis for a wide range of genetic …

Human diseases, especially infectious ones, have been evolving constantly. However, their
treatment strategies are not develo** quickly. Some diseases are caused by a variety of …

Genomics, epigenomics, transcriptomics, proteomics and metabolomics efforts rapidly
generate a plethora of data on the activity and levels of biomolecules within mammalian …

In silico reuse of old drugs (also known as drug repositioning) to treat common and rare
diseases is increasingly becoming an attractive proposition because it involves the use of de …

Motivation: Drug repositioning, which aims to identify new indications for existing drugs,
offers a promising alternative to reduce the total time and cost of traditional drug …

Genome-wide association studies have greatly improved our understanding of the genetic
basis of disease risk. The fact that they tend not to identify more than a fraction of the specific …

Motivation Computational drug repositioning is an important and efficient approach towards
identifying novel treatments for diseases in drug discovery. The emergence of large-scale …